PTRC_LACCA
ID PTRC_LACCA Reviewed; 277 AA.
AC Q9RGG3;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=PTS system sorbose-specific EIIC component {ECO:0000303|PubMed:10613875};
DE AltName: Full=EIIC-Sor {ECO:0000303|PubMed:10613875};
DE AltName: Full=Sorbose permease IIC component {ECO:0000303|PubMed:10613875};
GN Name=sorC {ECO:0000303|PubMed:10613875};
OS Lactobacillus casei.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1582;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND INDUCTION.
RC STRAIN=ATCC 393 / DSM 20011 / BCRC 10697 / JCM 1134 / NBRC 15883 / NCIMB
RC 11970 / NCDO 161 / WDCM 00100;
RX PubMed=10613875; DOI=10.1128/jb.182.1.155-163.2000;
RA Yebra M.J., Veyrat A., Santos M.A., Perez-Martinez G.;
RT "Genetics of L-sorbose transport and metabolism in Lactobacillus casei.";
RL J. Bacteriol. 182:155-163(2000).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (PTS), a major carbohydrate active transport system, catalyzes
CC the phosphorylation of incoming sugar substrates concomitant with their
CC translocation across the cell membrane. The enzyme II SorABCD PTS
CC system is involved in L-sorbose transport.
CC {ECO:0000269|PubMed:10613875}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00429}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00429}.
CC -!- INDUCTION: Induced by L-sorbose and repressed by D-glucose.
CC {ECO:0000269|PubMed:10613875}.
CC -!- DOMAIN: The EIIC type-4 domain forms the PTS system translocation
CC channel and contains the specific substrate-binding site.
CC {ECO:0000255|PROSITE-ProRule:PRU00429}.
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DR EMBL; AF129168; AAF24133.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9RGG3; -.
DR SMR; Q9RGG3; -.
DR STRING; 543734.LCABL_04270; -.
DR TCDB; 4.A.6.1.26; the pts mannose-fructose-sorbose (man) family.
DR eggNOG; COG3715; Bacteria.
DR BRENDA; 2.7.1.206; 2854.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR InterPro; IPR004700; PTS_IIC_man.
DR Pfam; PF03609; EII-Sor; 1.
DR TIGRFAMs; TIGR00822; EII-Sor; 1.
DR PROSITE; PS51106; PTS_EIIC_TYPE_4; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Phosphotransferase system; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..277
FT /note="PTS system sorbose-specific EIIC component"
FT /id="PRO_0000437532"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
FT DOMAIN 3..237
FT /note="PTS EIIC type-4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00429"
SQ SEQUENCE 277 AA; 29002 MW; EB7869F899621644 CRC64;
MAISTIQIIL IFIWSSVVGM GSVLDEFQTH RPLIACSIMG LILGDPKTGI ILGGTLELIA
LGWMNIGAAQ SPDSALASTI STILVIVGNQ DIQKGIAIAL PVAAAGQVLT VLARTVTVAF
QHAADREAEK ANFTAIIWLH FTALIVQALR VSIPTTIVAV FVSPEEIKSM LDALPEVITG
GLAVAGGFIV VVGYAMILNM MSVKYLMPFF YQGFVLGGYL KLSLLAWGAV GLIFAIVYVQ
LNPKFATNHN NGTGGSGGTV AAAGDHPAAL PEDELDD
