ID   PTRD1_BOVIN             Reviewed;         140 AA.
AC   Q3SZ85;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Putative peptidyl-tRNA hydrolase PTRHD1;
DE            EC=3.1.1.29;
DE   AltName: Full=Peptidyl-tRNA hydrolase domain-containing protein 1;
GN   Name=PTRHD1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-140.
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-
CC         amino acid + H(+); Xref=Rhea:RHEA:54448, Rhea:RHEA-COMP:10123,
CC         Rhea:RHEA-COMP:13883, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:59874, ChEBI:CHEBI:78442, ChEBI:CHEBI:138191;
CC         EC=3.1.1.29;
CC   -!- SIMILARITY: Belongs to the PTH2 family. PTRHD1 subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI03056.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AAFC03015212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC103055; AAI03056.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001030568.1; NM_001035491.2.
DR   AlphaFoldDB; Q3SZ85; -.
DR   SMR; Q3SZ85; -.
DR   STRING; 9913.ENSBTAP00000019984; -.
DR   PaxDb; Q3SZ85; -.
DR   PRIDE; Q3SZ85; -.
DR   Ensembl; ENSBTAT00000019984; ENSBTAP00000019984; ENSBTAG00000015012.
DR   GeneID; 617088; -.
DR   KEGG; bta:617088; -.
DR   CTD; 391356; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015012; -.
DR   VGNC; VGNC:33563; PTRHD1.
DR   eggNOG; KOG3305; Eukaryota.
DR   GeneTree; ENSGT00500000044959; -.
DR   HOGENOM; CLU_119261_0_1_1; -.
DR   InParanoid; Q3SZ85; -.
DR   OMA; CLALKPC; -.
DR   OrthoDB; 1557083at2759; -.
DR   TreeFam; TF353726; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000015012; Expressed in oocyte and 107 other tissues.
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1490.10; -; 1.
DR   InterPro; IPR023476; Pep_tRNA_hydro_II_dom_sf.
DR   InterPro; IPR002833; PTH2.
DR   InterPro; IPR042237; PTRHD1.
DR   PANTHER; PTHR46194; PTHR46194; 1.
DR   Pfam; PF01981; PTH2; 1.
DR   SUPFAM; SSF102462; SSF102462; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..140
FT                   /note="Putative peptidyl-tRNA hydrolase PTRHD1"
FT                   /id="PRO_0000321817"
SQ   SEQUENCE   140 AA;  15973 MW;  BBAC1129B8F38C02 CRC64;
     MHRGVGPAFQ LSRKMAASGG EPQILVQYLV LRKDLTQPPF SWPAGAVVAQ ACHAATAALH
     LHRDHPHTAA YLRELERMRK VVLEAPDETT LKLLAETLQQ KNIDHKLWME QPENIPTCIA
     LRPYPKEEVS QYLKKFRLFK