ID   PTRD_KLEPN              Reviewed;         274 AA.
AC   P37083;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=PTS system sorbose-specific EIID component {ECO:0000303|PubMed:2287279};
DE   AltName: Full=EIID-Sor {ECO:0000303|PubMed:2287279};
DE   AltName: Full=Sorbose permease IID component {ECO:0000303|PubMed:2287279};
GN   Name=sorM {ECO:0000303|PubMed:2287279};
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=1033-5P14 / KAY2026;
RX   PubMed=7947968; DOI=10.1016/0167-4838(94)90124-4;
RA   Wehmeier U.F., Lengeler J.W.;
RT   "Sequence of the sor-operon for L-sorbose utilization from Klebsiella
RT   pneumoniae KAY2026.";
RL   Biochim. Biophys. Acta 1208:348-351(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7700234; DOI=10.1007/bf00298968;
RA   Wehmeier U.F., Wohrl B.M., Lengeler J.W.;
RT   "Molecular analysis of the phosphoenolpyruvate-dependent L-sorbose:
RT   phosphotransferase system from Klebsiella pneumoniae and of its multidomain
RT   structure.";
RL   Mol. Gen. Genet. 246:610-618(1995).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RC   STRAIN=1033-5P14 / KAY2026;
RX   PubMed=6361004; DOI=10.1128/jb.157.1.39-45.1984;
RA   Sprenger G.A., Lengeler J.W.;
RT   "L-Sorbose metabolism in Klebsiella pneumoniae and Sor+ derivatives of
RT   Escherichia coli K-12 and chemotaxis toward sorbose.";
RL   J. Bacteriol. 157:39-45(1984).
RN   [4]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=2287279; DOI=10.1111/j.1365-2958.1990.tb02067.x;
RA   Woehrl B.M., Lengeler J.W.;
RT   "Cloning and physical mapping of the sor genes for L-sorbose transport and
RT   metabolism from Klebsiella pneumoniae.";
RL   Mol. Microbiol. 4:1557-1565(1990).
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane. The enzyme II SorABFM PTS
CC       system is involved in sorbose transport. {ECO:0000269|PubMed:6361004,
CC       ECO:0000305|PubMed:2287279, ECO:0000305|PubMed:7700234}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:6361004};
CC       Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00431}.
CC   -!- INDUCTION: By L-sorbose. {ECO:0000269|PubMed:2287279}.
CC   -!- DOMAIN: The EIID domain, with its homologous EIIC domain, forms the PTS
CC       system translocation channel and contains part of its specific
CC       substrate-binding site. {ECO:0000255|PROSITE-ProRule:PRU00431}.
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DR   EMBL; X66059; CAA46860.1; -; Genomic_DNA.
DR   PIR; S50190; S50190.
DR   AlphaFoldDB; P37083; -.
DR   SMR; P37083; -.
DR   TCDB; 4.A.6.1.3; the pts mannose-fructose-sorbose (man) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   InterPro; IPR004704; PTS_IID_man.
DR   Pfam; PF03613; EIID-AGA; 1.
DR   TIGRFAMs; TIGR00828; EIID-AGA; 1.
DR   PROSITE; PS51108; PTS_EIID; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Phosphotransferase system;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..274
FT                   /note="PTS system sorbose-specific EIID component"
FT                   /id="PRO_0000186664"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT   DOMAIN          4..273
FT                   /note="PTS EIID"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
SQ   SEQUENCE   274 AA;  29196 MW;  91C2E415ACBDE960 CRC64;
     MEQKKITQGD LVSMFLRSNL QQASFNFERI HGLGFCYDMI PAIKRLYPLK ADQVAALKRH
     LVFFNTTPAV CGPVIAVTAA MEEARANGAA IDDGAINGIK VGLMGPLAGV GDPLVWGTLR
     PITAALGASL ALSGNILGPL LFFFIFNAVR LAMKWYGLQL GFRKGVNIVS DMGGNLLQKL
     TEGASILGLF VMGVLVTKWT TINVPLVVSQ TPGADGATVT MTVQNILDQL CPGLLALGLT
     LLMVRLLNKK VNPVWLIFAL FGLGIIGNAL GFLS