PTRD_LACCA
ID PTRD_LACCA Reviewed; 282 AA.
AC Q9RGG2; F2M4V2;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=PTS system sorbose-specific EIID component {ECO:0000303|PubMed:10613875};
DE AltName: Full=EIID-Sor {ECO:0000303|PubMed:10613875};
DE AltName: Full=Sorbose permease IID component {ECO:0000303|PubMed:10613875};
GN Name=sorD {ECO:0000303|PubMed:10613875};
OS Lactobacillus casei.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1582;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 393 / DSM 20011 / BCRC 10697 / JCM 1134 / NBRC 15883 / NCIMB
RC 11970 / NCDO 161 / WDCM 00100;
RX PubMed=10613875; DOI=10.1128/jb.182.1.155-163.2000;
RA Yebra M.J., Veyrat A., Santos M.A., Perez-Martinez G.;
RT "Genetics of L-sorbose transport and metabolism in Lactobacillus casei.";
RL J. Bacteriol. 182:155-163(2000).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (PTS), a major carbohydrate active transport system, catalyzes
CC the phosphorylation of incoming sugar substrates concomitant with their
CC translocation across the cell membrane. The enzyme II SorABCD PTS
CC system is involved in L-sorbose transport.
CC {ECO:0000269|PubMed:10613875}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00431}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00431}.
CC -!- INDUCTION: Induced by L-sorbose and repressed by D-glucose.
CC {ECO:0000269|PubMed:10613875}.
CC -!- DOMAIN: The EIID domain, with its homologous EIIC domain, forms the PTS
CC system translocation channel and contains part of its specific
CC substrate-binding site. {ECO:0000255|PROSITE-ProRule:PRU00431}.
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DR EMBL; AF129168; AAF24134.1; -; Genomic_DNA.
DR RefSeq; WP_012490966.1; NZ_MODT01000074.1.
DR AlphaFoldDB; Q9RGG2; -.
DR SMR; Q9RGG2; -.
DR STRING; 543734.LCABL_04280; -.
DR TCDB; 4.A.6.1.26; the pts mannose-fructose-sorbose (man) family.
DR eggNOG; COG3716; Bacteria.
DR OMA; GDSFFWH; -.
DR BRENDA; 2.7.1.206; 2854.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR InterPro; IPR004704; PTS_IID_man.
DR Pfam; PF03613; EIID-AGA; 1.
DR TIGRFAMs; TIGR00828; EIID-AGA; 1.
DR PROSITE; PS51108; PTS_EIID; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Phosphotransferase system; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..282
FT /note="PTS system sorbose-specific EIID component"
FT /id="PRO_0000437533"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
FT DOMAIN 13..281
FT /note="PTS EIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00431"
SQ SEQUENCE 282 AA; 30788 MW; 53896526296B76DB CRC64;
MADQPVQVNK LKTKITKGDM FKTFVFENFQ QASFNFERIH ALAFCVDMIP TIKRVYSKKE
DQVAALKRHL VFFNTTPAMC GPIVGVTMAL EEGRAAGEPI DDGTINSFKV GLMGPLAGVG
DPLMWGTLRP ILAALGASLA LQGSWLGPIL FFVAFNAVRL SLKWYGLQLG FSRGLALVKD
MSGNLLQKIT EGATVLGLFI MGILVTKWTT INVPLVVSKT TVNGKTTVTT LQNILDQFCP
GLLALGWTLL CMYLLRKKVS PILLIFALFG VGIVGYWLGI LK
