ATP6B_ARATH
ID ATP6B_ARATH Reviewed; 55 AA.
AC P0DO45; A0A178V8C6; Q9SN96;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 23-FEB-2022, sequence version 1.
DT 03-AUG-2022, entry version 3.
DE RecName: Full=ATP synthase small subunit 6-B, mitochondrial {ECO:0000303|PubMed:23096681};
DE Short=AtMtATP6 {ECO:0000303|PubMed:23096681};
DE Short=MtATP6 {ECO:0000303|PubMed:23096681};
DE AltName: Full=ATP synthase 6 kDa subunit, mitochondrial {ECO:0000305};
DE Flags: Precursor;
GN Name=ATP6 {ECO:0000303|PubMed:23096681};
GN OrderedLocusNames=At5g59613 {ECO:0000312|Araport:AT5G59613};
GN ORFNames=MTH12.17 {ECO:0000312|EMBL:AAL32914.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, AND INDUCTION BY ABIOTIC STRESSES.
RX PubMed=23096681; DOI=10.4238/2012.october.4.3;
RA Moghadam A.A., Taghavi S.M., Niazi A., Djavaheri M., Ebrahimie E.;
RT "Isolation and in silico functional analysis of MtATP6, a 6-kDa subunit of
RT mitochondrial F(1)F0-ATP synthase, in response to abiotic stress.";
RL Genet. Mol. Res. 11:3547-3567(2012).
CC -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or
CC Complex V) produces ATP from ADP in the presence of a proton gradient
CC across the membrane which is generated by electron transport complexes
CC of the respiratory chain (Probable). F-type ATPases consist of two
CC structural domains, F(1) - containing the extramembraneous catalytic
CC core and F(0) - containing the membrane proton channel, linked together
CC by a central stalk and a peripheral stalk (Probable). During catalysis,
CC ATP synthesis in the catalytic domain of F(1) is coupled via a rotary
CC mechanism of the central stalk subunits to proton translocation
CC (Probable). Part of the complex F(0) domain (Probable). Confers
CC tolerance to several abiotic stresses (e.g. salt, mannitol, drought,
CC oxidative and cold stresses), probably by providing additional energy
CC needed for cell homeostasis (PubMed:23096681).
CC {ECO:0000269|PubMed:23096681, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:P0DO44}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ATPase 6 subunit family. {ECO:0000305}.
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DR EMBL; AB006705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED97213.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97214.1; -; Genomic_DNA.
DR EMBL; AK118417; BAC43026.1; -; mRNA.
DR EMBL; AY062836; AAL32914.1; -; mRNA.
DR SMR; P0DO45; -.
DR Araport; AT5G59613; -.
DR Proteomes; UP000006548; Chromosome 5.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0009409; P:response to cold; IDA:UniProtKB.
DR GO; GO:1902074; P:response to salt; IDA:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IDA:UniProtKB.
PE 2: Evidence at transcript level;
KW CF(0); Hydrogen ion transport; Ion transport; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Stress response;
KW Transit peptide; Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..11
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 12..55
FT /note="ATP synthase small subunit 6-B, mitochondrial"
FT /id="PRO_0000454201"
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 55 AA; 6585 MW; 96CEA6088EEBAA32 CRC64;
MRLFDPWPVF FKREWKRCWP FLTGFAVTGV LITKLTAGLT EEDAKNSKFV QQHRR
