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PUB11_ARATH
ID   PUB11_ARATH             Reviewed;         612 AA.
AC   Q8GUG9; O23121; Q56WV7;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=U-box domain-containing protein 11;
DE            EC=2.3.2.27;
DE   AltName: Full=Plant U-box protein 11;
DE   AltName: Full=RING-type E3 ubiquitin transferase PUB11 {ECO:0000305};
GN   Name=PUB11; OrderedLocusNames=At1g23030; ORFNames=F10G19.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 263-612.
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=11495788; DOI=10.1016/s1360-1385(01)01960-4;
RA   Azevedo C., Santos-Rosa M.J., Shirasu K.;
RT   "The U-box protein family in plants.";
RL   Trends Plant Sci. 6:354-358(2001).
RN   [6]
RP   GENE FAMILY ORGANIZATION.
RX   PubMed=14657406; DOI=10.1104/pp.103.029553;
RA   Mudgil Y., Shiu S.-H., Stone S.L., Salt J.N., Goring D.R.;
RT   "A large complement of the predicted Arabidopsis ARM repeat proteins are
RT   members of the U-box E3 ubiquitin ligase family.";
RL   Plant Physiol. 134:59-66(2004).
CC   -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27;
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB72157.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AF000657; AAB72157.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE30324.1; -; Genomic_DNA.
DR   EMBL; BT002518; AAO00878.1; -; mRNA.
DR   EMBL; AK221923; BAD94341.1; -; mRNA.
DR   PIR; D86364; D86364.
DR   RefSeq; NP_173716.1; NM_102151.5.
DR   AlphaFoldDB; Q8GUG9; -.
DR   SMR; Q8GUG9; -.
DR   STRING; 3702.AT1G23030.1; -.
DR   PaxDb; Q8GUG9; -.
DR   PRIDE; Q8GUG9; -.
DR   EnsemblPlants; AT1G23030.1; AT1G23030.1; AT1G23030.
DR   GeneID; 838911; -.
DR   Gramene; AT1G23030.1; AT1G23030.1; AT1G23030.
DR   KEGG; ath:AT1G23030; -.
DR   Araport; AT1G23030; -.
DR   TAIR; locus:2017719; AT1G23030.
DR   eggNOG; KOG0167; Eukaryota.
DR   HOGENOM; CLU_006348_5_1_1; -.
DR   InParanoid; Q8GUG9; -.
DR   OMA; GYINGRT; -.
DR   OrthoDB; 308896at2759; -.
DR   PhylomeDB; Q8GUG9; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q8GUG9; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8GUG9; baseline and differential.
DR   Genevisible; Q8GUG9; AT.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IDA:TAIR.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:TAIR.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:TAIR.
DR   GO; GO:0090333; P:regulation of stomatal closure; IMP:TAIR.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.25.10.10; -; 1.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF00514; Arm; 2.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00185; ARM; 5.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 3.
DR   PROSITE; PS51698; U_BOX; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Repeat; Transferase;
KW   Ubl conjugation pathway.
FT   CHAIN           1..612
FT                   /note="U-box domain-containing protein 11"
FT                   /id="PRO_0000322156"
FT   DOMAIN          240..314
FT                   /note="U-box"
FT   REPEAT          363..402
FT                   /note="ARM 1"
FT   REPEAT          404..443
FT                   /note="ARM 2"
FT   REPEAT          445..484
FT                   /note="ARM 3"
FT   REPEAT          486..526
FT                   /note="ARM 4"
FT   REPEAT          528..567
FT                   /note="ARM 5"
FT   COILED          127..196
FT                   /evidence="ECO:0000255"
FT   CONFLICT        67
FT                   /note="W -> C (in Ref. 3; AAO00878)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   612 AA;  67356 MW;  E0C2963C7953CF82 CRC64;
     MAGGIVSPAS LLDLIADIVE IPLNTGMFKK DCADLTRRVC LLTHLLEEIR DSTPIDSAAS
     SSSENDWWSD LVVGLQAAKR LLSTARFQAR DSSDGAAKRI SFQFQCVTWK LEKALSNLPY
     DLYDISDEVG EQVELARSQL RRAMQRYGSL NSNKFSSALS EPMERDGFSN VIKIKAEEKL
     ESVSETLHFG EEEEKQSSPP LRRSSSISLA YYLSKDADTD RLDKMVNKNT DESKKSDKLT
     IPVDFLCPVS LELMKDPVIV ATGQTYERAY IQRWIDCGNL TCPKTQQKLE NFTLTPNYVL
     RSLISRWCAE HNIEQPAGYI NGRTKNSGDM SVIRALVQRL SSRSTEDRRN AVSEIRSLSK
     RSTDNRILIA EAGAIPVLVN LLTSEDVATQ ENAITCVLNL SIYENNKELI MFAGAVTSIV
     QVLRAGTMEA RENAAATLFS LSLADENKII IGGSGAIPAL VDLLENGTPR GKKDAATALF
     NLCIYHGNKG RAVRAGIVTA LVKMLSDSTR HRMVDEALTI LSVLANNQDA KSAIVKANTL
     PALIGILQTD QTRNRENAAA ILLSLCKRDT EKLITIGRLG AVVPLMDLSK NGTERGKRKA
     ISLLELLRKA CQ
 
 
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