PUB36_ARATH
ID PUB36_ARATH Reviewed; 435 AA.
AC Q8GZ84; Q9M2C5;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=U-box domain-containing protein 36;
DE EC=2.3.2.27;
DE AltName: Full=Plant U-box protein 36;
DE AltName: Full=RING-type E3 ubiquitin transferase PUB36 {ECO:0000305};
GN Name=PUB36; OrderedLocusNames=At3g61390; ORFNames=F2A19.1, T20K12.290;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11495788; DOI=10.1016/s1360-1385(01)01960-4;
RA Azevedo C., Santos-Rosa M.J., Shirasu K.;
RT "The U-box protein family in plants.";
RL Trends Plant Sci. 6:354-358(2001).
CC -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27;
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q8GZ84-1; Sequence=Displayed;
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB71069.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL132962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL137898; CAB71069.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE80195.1; -; Genomic_DNA.
DR EMBL; AK117154; BAC41832.1; -; mRNA.
DR EMBL; BT005367; AAO63431.1; -; mRNA.
DR PIR; T47931; T47931.
DR RefSeq; NP_191698.2; NM_116003.3. [Q8GZ84-1]
DR AlphaFoldDB; Q8GZ84; -.
DR PaxDb; Q8GZ84; -.
DR EnsemblPlants; AT3G61390.2; AT3G61390.2; AT3G61390. [Q8GZ84-1]
DR GeneID; 825311; -.
DR Gramene; AT3G61390.2; AT3G61390.2; AT3G61390. [Q8GZ84-1]
DR KEGG; ath:AT3G61390; -.
DR Araport; AT3G61390; -.
DR TAIR; locus:2098816; AT3G61390.
DR eggNOG; ENOG502SN9F; Eukaryota.
DR HOGENOM; CLU_036548_0_0_1; -.
DR InParanoid; Q8GZ84; -.
DR OMA; EKICIEM; -.
DR OrthoDB; 936010at2759; -.
DR PhylomeDB; Q8GZ84; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q8GZ84; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8GZ84; baseline and differential.
DR Genevisible; Q8GZ84; AT.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR Gene3D; 3.40.50.620; -; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome; Transferase;
KW Ubl conjugation pathway.
FT CHAIN 1..435
FT /note="U-box domain-containing protein 36"
FT /id="PRO_0000322176"
FT DOMAIN 352..426
FT /note="U-box"
FT COILED 227..345
FT /evidence="ECO:0000255"
FT CONFLICT 181
FT /note="Missing (in Ref. 3; BAC41832 and 4; AAO63431)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 435 AA; 50513 MW; 43165A7BCBED8103 CRC64;
MTLKIPIQEM VKMVGSLRSH GIDIPESMEI NKKEKIYVAV TEKDLESKSS LVWAIQNSGG
KEFCIVHVHQ PIPGEMFHEQ KLRLYRKEKD KAHKNSEKYL QICRQMQVTA EIIYIETDSV
EKGILQLISQ RGVTKLVMGA AADRHYSMRM RDLKSKKAIY IHREAPATCL IWFTCNGYLI
CSREARRANN LYLECASSNS LSQSDITRGT ESIVKDDDHL IKLAVTEAEA SKRKARFEAC
KREEAEKTAV DALKKAKQWE NVYFEELKQR KETEKALRKR NDELEKMRSE SETQITESYT
VIRKLQEKNN LSMETFRGIR EEQEELKIKL REVSKLKGKR EEEEASTSNH REPPQYFICP
ITHDIMEDPH VAADGFTYEG EAISRWFERG HETSPMINKR LPHTSLVPNL ALRSAIQEWL
QLRELLNRPS ACREI
