PUB37_ARATH
ID PUB37_ARATH Reviewed; 400 AA.
AC Q683D5; O80827;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=U-box domain-containing protein 37;
DE EC=2.3.2.27;
DE AltName: Full=Plant U-box protein 37;
DE AltName: Full=RING-type E3 ubiquitin transferase PUB37 {ECO:0000305};
GN Name=PUB37; OrderedLocusNames=At2g45920; ORFNames=F4I18.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11495788; DOI=10.1016/s1360-1385(01)01960-4;
RA Azevedo C., Santos-Rosa M.J., Shirasu K.;
RT "The U-box protein family in plants.";
RL Trends Plant Sci. 6:354-358(2001).
CC -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27;
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC28533.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC004665; AAC28533.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC10617.1; -; Genomic_DNA.
DR EMBL; AK175182; BAD42945.1; -; mRNA.
DR EMBL; BT015764; AAU90054.1; -; mRNA.
DR EMBL; BT020181; AAV43783.1; -; mRNA.
DR PIR; T02455; T02455.
DR RefSeq; NP_182116.2; NM_130155.5.
DR AlphaFoldDB; Q683D5; -.
DR SMR; Q683D5; -.
DR BioGRID; 4536; 6.
DR IntAct; Q683D5; 6.
DR PaxDb; Q683D5; -.
DR PRIDE; Q683D5; -.
DR EnsemblPlants; AT2G45920.1; AT2G45920.1; AT2G45920.
DR GeneID; 819200; -.
DR Gramene; AT2G45920.1; AT2G45920.1; AT2G45920.
DR KEGG; ath:AT2G45920; -.
DR Araport; AT2G45920; -.
DR TAIR; locus:2050659; AT2G45920.
DR eggNOG; ENOG502S95A; Eukaryota.
DR HOGENOM; CLU_036548_0_0_1; -.
DR InParanoid; Q683D5; -.
DR OMA; NTRGREF; -.
DR OrthoDB; 957291at2759; -.
DR PhylomeDB; Q683D5; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q683D5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q683D5; baseline and differential.
DR Genevisible; Q683D5; AT.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Transferase; Ubl conjugation pathway.
FT CHAIN 1..400
FT /note="U-box domain-containing protein 37"
FT /id="PRO_0000322177"
FT DOMAIN 324..398
FT /note="U-box"
FT COILED 229..298
FT /evidence="ECO:0000255"
SQ SEQUENCE 400 AA; 46024 MW; 1CA0A2D447D7E8E5 CRC64;
MMGKSGSQQL LMDEKIYVAV GSDLGNKSTL VWAIQNTGGK EFCIVHVHQP LYRKEKEKTQ
KILDKYLQKC RQMQVCAEMI HIKMESVEKG IIQLISERNV KKLVMGAASD TRYSMRMADL
LSTKAIYIRQ EAPATCCIWF TCKGYLVYKR ESIMGNTSLE YASTSSGQDS VRSRGSVIPS
RQFTISRGNG NVYQLAVFEA EKSKKEASLE AFKHQEVVKE KNEAIKRGKE WESAYLEELK
QRKETEMELK KVREKLEKMR YISENRITES YMLVQKLQDK YNLATKVLRK AKEERDLLIK
GRDIAIIEVE ELRKEVSRSD EHREAPQYFI CPISLEVMKD PQLAADGFTY EAEAISTWLQ
GGHETSPMTN TKLHHTKLVP NLALRSAIQE WLHASSSFRK
