PUB39_ARATH
ID PUB39_ARATH Reviewed; 531 AA.
AC Q9STT1; Q8RWZ2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 31-JAN-2018, sequence version 2.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=U-box domain-containing protein 39;
DE EC=2.3.2.27;
DE AltName: Full=Plant U-box protein 39;
DE AltName: Full=RING-type E3 ubiquitin transferase PUB39 {ECO:0000305};
GN Name=PUB39; OrderedLocusNames=At3g47820; ORFNames=T23J7.150;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 21-531.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 23-531.
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY ORGANIZATION.
RX PubMed=14657406; DOI=10.1104/pp.103.029553;
RA Mudgil Y., Shiu S.-H., Stone S.L., Salt J.N., Goring D.R.;
RT "A large complement of the predicted Arabidopsis ARM repeat proteins are
RT members of the U-box E3 ubiquitin ligase family.";
RL Plant Physiol. 134:59-66(2004).
CC -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27;
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- INTERACTION:
CC Q9STT1; Q9SZU7: KAI2; NbExp=3; IntAct=EBI-25530170, EBI-25519488;
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB41865.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL049746; CAB41865.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE78334.2; -; Genomic_DNA.
DR EMBL; AY091018; AAM14040.1; -; mRNA.
DR EMBL; BT020355; AAV85710.1; -; mRNA.
DR PIR; T07721; T07721.
DR RefSeq; NP_190366.2; NM_114650.3.
DR AlphaFoldDB; Q9STT1; -.
DR SMR; Q9STT1; -.
DR BioGRID; 9256; 1.
DR IntAct; Q9STT1; 1.
DR STRING; 3702.AT3G47820.1; -.
DR iPTMnet; Q9STT1; -.
DR PaxDb; Q9STT1; -.
DR PRIDE; Q9STT1; -.
DR ProteomicsDB; 226246; -.
DR EnsemblPlants; AT3G47820.1; AT3G47820.1; AT3G47820.
DR GeneID; 823936; -.
DR Gramene; AT3G47820.1; AT3G47820.1; AT3G47820.
DR KEGG; ath:AT3G47820; -.
DR Araport; AT3G47820; -.
DR TAIR; locus:2100372; AT3G47820.
DR eggNOG; ENOG502QPJU; Eukaryota.
DR HOGENOM; CLU_006348_7_0_1; -.
DR InParanoid; Q9STT1; -.
DR OMA; FHHHRSA; -.
DR OrthoDB; 425663at2759; -.
DR PhylomeDB; Q9STT1; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9STT1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9STT1; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 1.25.10.10; -; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00514; Arm; 2.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat; Transferase; Ubl conjugation pathway.
FT CHAIN 1..531
FT /note="U-box domain-containing protein 39"
FT /id="PRO_0000322179"
FT DOMAIN 31..105
FT /note="U-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01034"
FT REPEAT 237..276
FT /note="ARM 1"
FT /evidence="ECO:0000255"
FT REPEAT 278..317
FT /note="ARM 2"
FT /evidence="ECO:0000255"
FT REPEAT 319..359
FT /note="ARM 3"
FT /evidence="ECO:0000255"
FT REPEAT 361..401
FT /note="ARM 4"
FT /evidence="ECO:0000255"
FT REPEAT 403..444
FT /note="ARM 5"
FT /evidence="ECO:0000255"
FT REPEAT 447..488
FT /note="ARM 6"
FT /evidence="ECO:0000255"
FT REGION 167..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 57638 MW; CCB13B15CFF8888D CRC64;
MGDTGRHKWF SFHHHRSASA TTMPQHNSPG ETPTEFLCPI TGFLMSDPVV VASGQTFERI
SVQVCRNLSF APKLHDGTQP DLSTVIPNLA MKSTILSWCD RNKMEHPRPP DYAYVEGVVR
TRMDSLPPGS GHRIAKSEIL PPVAENSNSN SDYDSVMGAI RSRSRTSLSS TTSLPLHQTR
PINHSTRIQS SFSTSDYSSF PPMSPEEEEI YNKLTSVDTI DHEQGLIQLR KTTRSNETTR
ISLCTDRILS LLRSLIVSRY NIVQTNAAAS IVNLSLEKPN KLKIVRSGFV PLLIDVLKSG
STEAQEHVIG ALFSLAVEEE NKMVIGVLGA VEPLLHALRS SESERARQDA ALALYHLSLI
PNNRSRLVKA GAVPMMLSMI RSGESASRIL LLLCNLAACS EGKGAMLDGN AVSILVGKLR
ESGGAESDAA ARENCVGALL TLSVGNMRFR GLASEAGAEE ILTEIVESES GSGRLKEKAS
KILQTLRGGG SEFGEGAEAR EWNRMLEASG LSRSQFQQGG QKGGFAYSSQ F
