ID   PUB62_ARATH             Reviewed;         363 AA.
AC   Q6DBN5; Q9FLD1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=U-box domain-containing protein 62;
DE            EC=2.3.2.27;
DE   AltName: Full=Plant U-box protein 62;
DE   AltName: Full=RING-type E3 ubiquitin transferase PUB62 {ECO:0000305};
GN   Name=PUB62; OrderedLocusNames=At5g05230; ORFNames=K18I23.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27;
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB09966.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB010692; BAB09966.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED90844.1; -; Genomic_DNA.
DR   EMBL; BT014987; AAT70438.1; -; mRNA.
DR   EMBL; BT015849; AAU94412.1; -; mRNA.
DR   EMBL; AK228492; BAF00418.1; -; mRNA.
DR   RefSeq; NP_196142.3; NM_120605.4.
DR   AlphaFoldDB; Q6DBN5; -.
DR   PaxDb; Q6DBN5; -.
DR   PRIDE; Q6DBN5; -.
DR   ProteomicsDB; 226455; -.
DR   EnsemblPlants; AT5G05230.1; AT5G05230.1; AT5G05230.
DR   GeneID; 830405; -.
DR   Gramene; AT5G05230.1; AT5G05230.1; AT5G05230.
DR   KEGG; ath:AT5G05230; -.
DR   Araport; AT5G05230; -.
DR   TAIR; locus:2153484; AT5G05230.
DR   eggNOG; ENOG502QT2D; Eukaryota.
DR   HOGENOM; CLU_050611_0_0_1; -.
DR   InParanoid; Q6DBN5; -.
DR   OMA; HPHLEFR; -.
DR   OrthoDB; 983154at2759; -.
DR   PhylomeDB; Q6DBN5; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q6DBN5; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q6DBN5; baseline and differential.
DR   Genevisible; Q6DBN5; AT.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF04564; U-box; 1.
DR   PROSITE; PS51698; U_BOX; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Transferase; Ubl conjugation pathway.
FT   CHAIN           1..363
FT                   /note="U-box domain-containing protein 62"
FT                   /id="PRO_0000322194"
FT   DOMAIN          181..253
FT                   /note="U-box"
FT   REGION          74..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..106
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   363 AA;  39371 MW;  00730D6F7F4C1A8A CRC64;
     MSGKGLSPAP FNAQPMIVQD ADPLRFRVGE QDPKTREFAA FIGDHRYFAA AAAAAAAANP
     HPHLEFRQNF YSEKPIIGNP NDSGGSDGED DVDVEEEDED DDLDGNEGDI GMNKDAGEDS
     VSAGAVIVVG QDNAAYYSQH FKTVEASFVS RNEESSIAAD NGCDFSGRRD LSSSSSNSIE
     SLRTILSDPT TGSLMADAMI LPCGHTFGAG GIEQVKQMKA CCTCSQPVSE DSITPNLTLR
     VAVQAFCREE NSQSNHPSKR KREGFDQERR AFGVTNHSGR SRNKSNHFPF AVADRVIIKG
     NKRTPPRFVG REAVVTTQCL NGWYVVKTLD NAESVKLQYR SLAKAPEDPS AKATPNKMVS
     NWL