PUC1_SCHPO
ID PUC1_SCHPO Reviewed; 359 AA.
AC P25009;
DT 01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-1992, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Cyclin puc1;
GN Name=puc1; ORFNames=SPBC19F5.01c, SPBP8B7.32c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1828291; DOI=10.1038/351245a0;
RA Forsburg S.L., Nurse P.;
RT "Identification of a G1-type cyclin puc1+ in the fission yeast
RT Schizosaccharomyces pombe.";
RL Nature 351:245-247(1991).
RN [2]
RP ERRATUM OF PUBMED:1828291.
RA Forsburg S.L., Nurse P.;
RL Nature 352:648-648(1991).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8006074;
RA Forsburg S.L., Nurse P.;
RT "Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role
RT in cell cycle exit.";
RL J. Cell Sci. 107:601-613(1994).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Function in exit from the mitotic cycle. Contributes to
CC negative regulation of the timing of sexual development in fission
CC yeast, and functions at the transition between cycling and non-cycling
CC cells. Interacts with protein kinase A.
CC -!- SIMILARITY: Belongs to the cyclin family. {ECO:0000305}.
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DR EMBL; X59154; CAA41868.1; -; Genomic_DNA.
DR EMBL; X74451; CAA52460.1; -; Genomic_DNA.
DR EMBL; CU329671; CAA21817.1; -; Genomic_DNA.
DR PIR; S15406; S15406.
DR PIR; S36408; S36408.
DR RefSeq; NP_596539.1; NM_001022460.2.
DR AlphaFoldDB; P25009; -.
DR SMR; P25009; -.
DR BioGRID; 277179; 22.
DR DIP; DIP-659N; -.
DR STRING; 4896.SPBC19F5.01c.1; -.
DR PaxDb; P25009; -.
DR EnsemblFungi; SPBC19F5.01c.1; SPBC19F5.01c.1:pep; SPBC19F5.01c.
DR PomBase; SPBC19F5.01c; puc1.
DR VEuPathDB; FungiDB:SPBC19F5.01c; -.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_771972_0_0_1; -.
DR InParanoid; P25009; -.
DR PhylomeDB; P25009; -.
DR Reactome; R-SPO-3214858; RMTs methylate histone arginines.
DR Reactome; R-SPO-5689880; Ub-specific processing proteases.
DR Reactome; R-SPO-5693607; Processing of DNA double-strand break ends.
DR Reactome; R-SPO-6804757; Regulation of TP53 Degradation.
DR Reactome; R-SPO-68949; Orc1 removal from chromatin.
DR Reactome; R-SPO-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR Reactome; R-SPO-69202; Cyclin E associated events during G1/S transition.
DR Reactome; R-SPO-69231; Cyclin D associated events in G1.
DR Reactome; R-SPO-69656; Cyclin A:Cdk2-associated events at S phase entry.
DR Reactome; R-SPO-75815; Ubiquitin-dependent degradation of Cyclin D.
DR Reactome; R-SPO-8951664; Neddylation.
DR Reactome; R-SPO-9754119; Drug-mediated inhibition of CDK4/CDK6 activity.
DR Reactome; R-SPO-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:P25009; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IGI:PomBase.
DR GO; GO:0044843; P:cell cycle G1/S phase transition; IMP:PomBase.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0110045; P:negative regulation of cell cycle switching, mitotic to meiotic cell cycle; IGI:PomBase.
DR GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; EXP:PomBase.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IGI:PomBase.
DR CDD; cd00043; CYCLIN; 1.
DR InterPro; IPR028857; CCNF_metazoan.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR014399; Cyclin_CLN.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR PANTHER; PTHR10177:SF252; PTHR10177:SF252; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001770; Cyclin_CLN; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..359
FT /note="Cyclin puc1"
FT /id="PRO_0000080418"
SQ SEQUENCE 359 AA; 40430 MW; 72DB0BB149041B4B CRC64;
MLVSSNEEQL TAHTPTSSSS IEPKILAACS YSLSVGPCSL AVSPKGVNSK SPSLKNETAF
VVDSVSTLSA ESSALLYNTQ SSLLTGLSMN GYLGEYQEDI IHHLITREKN FLLNVHLSNQ
QPELRWSMRP ALVNFIVEIH NGFDLSIDTL PLSISLMDSY VSRRVVYCKH IQLVACVCLW
IASKFHETED RVPLLQELKL ACKNIYAEDL FIRMERHILD TLDWDISIPT PASYIPVLDP
IFFLVLDASM FVPNLFKFPA SKIACSVMNI VNEHVGSFLL THPSMESYRK DDNFLWPEDL
DTVTSYMENM SKRYANEECT DLLFSSLGRI SSILAKKYPE QCAMAAWCNM TEKDTERTL
