PUP15_ARATH
ID PUP15_ARATH Reviewed; 387 AA.
AC Q9LQZ0; F4HZ42;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Putative purine permease 15;
DE Short=AtPUP15;
GN Name=PUP15; OrderedLocusNames=At1g75470; ORFNames=F10A5.31, F1B16.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10662864; DOI=10.2307/3870929;
RA Gillissen B., Buerkle L., Andre B., Kuehn C., Rentsch D., Brandl B.,
RA Frommer W.B.;
RT "A new family of high-affinity transporters for adenine, cytosine, and
RT purine derivatives in Arabidopsis.";
RL Plant Cell 12:291-300(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the purine permeases (TC 2.A.7.14) family.
CC {ECO:0000305}.
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DR EMBL; AC006434; AAF87123.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35724.2; -; Genomic_DNA.
DR RefSeq; NP_177680.2; NM_106201.2.
DR AlphaFoldDB; Q9LQZ0; -.
DR STRING; 3702.AT1G75470.1; -.
DR TCDB; 2.A.7.14.5; the drug/metabolite transporter (dmt) superfamily.
DR PaxDb; Q9LQZ0; -.
DR PRIDE; Q9LQZ0; -.
DR EnsemblPlants; AT1G75470.1; AT1G75470.1; AT1G75470.
DR GeneID; 843883; -.
DR Gramene; AT1G75470.1; AT1G75470.1; AT1G75470.
DR KEGG; ath:AT1G75470; -.
DR Araport; AT1G75470; -.
DR eggNOG; ENOG502QVMQ; Eukaryota.
DR HOGENOM; CLU_043459_2_1_1; -.
DR InParanoid; Q9LQZ0; -.
DR OMA; VTIIICT; -.
DR OrthoDB; 1684256at2759; -.
DR PhylomeDB; Q9LQZ0; -.
DR PRO; PR:Q9LQZ0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LQZ0; differential.
DR Genevisible; Q9LQZ0; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005345; F:purine nucleobase transmembrane transporter activity; IEA:UniProt.
DR GO; GO:0015211; F:purine nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR030182; PUP_plant.
DR PANTHER; PTHR31376; PTHR31376; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..387
FT /note="Putative purine permease 15"
FT /id="PRO_0000317402"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 387 AA; 43940 MW; C53DE2DE6CA8DBC9 CRC64;
MGHNQPMQSS NPQEHFVQIA LDIEHRLTTP ISLTSDSNQR RNQWVTIIIC TILAVTGQCI
ARLLENYYFL HKNLSRRRGI LTQTLLQVVG FPILLLPFLL HFLIKKQKQL LIFSGETSLK
HLAITYSILC IYMFCQAFFS DVRNQIPYRV FTLTYTTQLL FTLIFSKYYN DIKFNRWTFI
SLILAVLAGA FTLYTFSAGS PIYGKKSYGY GIINVAFGAA IFFSLLLCII RKVFEELISF
CNTSTNRKQP SFVVVLEMII FLSLVVTIIL VAAVLISGEH HDMKKEMETF TKGDIAYVRT
MVGQAVAWQI YWVGIVGLVF AVSAVFSNVI SVCTWPIVSL LVAFLYNTHD HFDVFRGIAL
GAAALSVSCY IYIIHKEKSD DDDQSTS
