PUP19_ARATH
ID PUP19_ARATH Reviewed; 392 AA.
AC Q9SX93; F4HV17;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Putative purine permease 19;
DE Short=AtPUP19;
GN Name=PUP19; OrderedLocusNames=At1g47603; ORFNames=F16N3.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10662864; DOI=10.2307/3870929;
RA Gillissen B., Buerkle L., Andre B., Kuehn C., Rentsch D., Brandl B.,
RA Frommer W.B.;
RT "A new family of high-affinity transporters for adenine, cytosine, and
RT purine derivatives in Arabidopsis.";
RL Plant Cell 12:291-300(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the purine permeases (TC 2.A.7.14) family.
CC {ECO:0000305}.
CC -!- CAUTION: The gene model predicted by TAIR differ by the presence of one
CC additional Glu at the splice site. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AEE32193.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007519; AAD46025.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32193.1; ALT_SEQ; Genomic_DNA.
DR PIR; H96516; H96516.
DR RefSeq; NP_001031153.1; NM_001036076.2.
DR AlphaFoldDB; Q9SX93; -.
DR STRING; 3702.AT1G47603.1; -.
DR PaxDb; Q9SX93; -.
DR PRIDE; Q9SX93; -.
DR GeneID; 3767386; -.
DR KEGG; ath:AT1G47603; -.
DR Araport; AT1G47603; -.
DR eggNOG; ENOG502QRUH; Eukaryota.
DR HOGENOM; CLU_043459_2_1_1; -.
DR InParanoid; Q9SX93; -.
DR OrthoDB; 750876at2759; -.
DR PhylomeDB; Q9SX93; -.
DR PRO; PR:Q9SX93; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SX93; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005345; F:purine nucleobase transmembrane transporter activity; IEA:UniProt.
DR GO; GO:0015211; F:purine nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR030182; PUP_plant.
DR PANTHER; PTHR31376; PTHR31376; 1.
PE 3: Inferred from homology;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..392
FT /note="Putative purine permease 19"
FT /id="PRO_0000317406"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 30
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9C508"
SQ SEQUENCE 392 AA; 43334 MW; 7F981E5F759828E0 CRC64;
MGFHTKSPDR VTHEEEANIG VDNQPRETTS TSLNRSQIIK TRNWWICIFV CSCLVVAGRV
LSTLLLNFYF IQTGRDVCDD PKQFKGTWLQ SMVQNAAFPF TAFLLLLWRS SFSTHSETSS
SSSSFGKLFL LYISLGVLFA AYSQLYAIGR THCVFFLWIF TSQLIFTSIF TTIINKQKFN
RWIILSMVLS GAATGLGITS SGGAYIPCEN EGSKMSNGAW CAFFGTVAFS LSLCIMQLGF
QKVIPTTQSR VSAVILMQTN ASMIATLICL VGLFVSGEFK DIKEDFETFK KGKPLYVLSL
IGLSLAWQVM SLGLVGLVCL ASSLFSNVVS FCSTPLVNIL LVLAFRFTDA DVKFFKEGAL
VAGILGFASY VYSLYKSTKK KEIASQSQTT RV
