PUT1_ORYSI
ID PUT1_ORYSI Reviewed; 531 AA.
AC A2X8M8;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Polyamine transporter PUT1;
DE AltName: Full=Polyamine uptake transporter 1;
DE Short=OsPUT1;
GN Name=PUT1; ORFNames=OsI_08590;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Cell membrane polyamine/proton symporter involved in the
CC polyamine uptake in cells. Possesses high affinity for spermidine and
CC lower affinity for spermine and putrescine. Transports paraquat, a
CC polyamine analog, and thus confers sensitivity to this chemical which
CC is used as herbicide (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}. Note=Plasma membrane.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
CC {ECO:0000305}.
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DR EMBL; CM000127; EAY87188.1; -; Genomic_DNA.
DR AlphaFoldDB; A2X8M8; -.
DR SMR; A2X8M8; -.
DR STRING; 39946.A2X8M8; -.
DR EnsemblPlants; BGIOSGA005787-TA; BGIOSGA005787-PA; BGIOSGA005787.
DR Gramene; BGIOSGA005787-TA; BGIOSGA005787-PA; BGIOSGA005787.
DR HOGENOM; CLU_007946_17_3_1; -.
DR OMA; PLIWIWL; -.
DR Proteomes; UP000007015; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015203; F:polyamine transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR044566; RMV1-like.
DR PANTHER; PTHR45826; PTHR45826; 1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..531
FT /note="Polyamine transporter PUT1"
FT /id="PRO_0000418914"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 476..496
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 56626 MW; BAE56BA6CD271EFE CRC64;
MADTGGRPEV SLATVRSPGH PAASTTAAAA ADLGHADTGQ EKPTVESAQP ANGAAPMGEC
GTEYRGLPDG DAGGPMPSSA RTVSMIPLIF LIFYEVSGGP FGIEDSVGAA GPLLAIIGFL
VLPVIWSIPE ALITAELGAM FPENGGYVVW VASALGPYWG FQQGWMKWLS GVIDNALYPV
LFLDYLKSGV PALGGGAPRA FAVVGLTAVL TLLNYRGLTV VGWVAICLGV FSLLPFFVMG
LIALPKLRPA RWLVIDLHNV DWNLYLNTLF WNLNYWDSIS TLAGEVKNPG KTLPKALFYA
VIFVVVAYLY PLLAGTGAVP LDRGQWTDGY FADIAKLLGG AWLMWWVQSA AALSNMGMFV
AEMSSDSYQL LGMAERGMLP SFFAARSRYG TPLAGILFSA SGVLLLSMMS FQEIVAAENF
LYCFGMLLEF VAFILHRVRR PDAARPYRVP LGTAGCVAML VPPTALIAVV LALSTLKVAV
VSLGAVAMGL VLQPALRFVE KKRWLRFSVN PDLPEIGVIR PPAAPDEPLV P
