PV42A_ARATH
ID PV42A_ARATH Reviewed; 352 AA.
AC Q9XI37;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=SNF1-related protein kinase regulatory subunit gamma-like PV42a;
DE Short=AtPV42a;
DE AltName: Full=AKIN subunit gamma-like PV42a;
DE AltName: Full=CBS domain-containing protein CBSCBS4;
GN Name=PV42A; Synonyms=CBSCBS4; OrderedLocusNames=At1g15330;
GN ORFNames=F9L1.27;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
RX PubMed=21533063; DOI=10.1371/journal.pone.0019033;
RA Fang L., Hou X., Lee L.Y., Liu L., Yan X., Yu H.;
RT "AtPV42a and AtPV42b redundantly regulate reproductive development in
RT Arabidopsis thaliana.";
RL PLoS ONE 6:E19033-E19033(2011).
CC -!- FUNCTION: Plays redundant role with PV42b in regulating male
CC gametogenesis and pollen tube guidance. {ECO:0000269|PubMed:21533063}.
CC -!- TISSUE SPECIFICITY: Expressed highly in rosette leaves, cauline leaves,
CC open flowers, developing siliques and dry seeds, but at a low level in
CC stems and floral buds. {ECO:0000269|PubMed:21533063}.
CC -!- DISRUPTION PHENOTYPE: Shorter siliques and reduced seed sets in pv42a
CC and pv42b RNAi double mutant. {ECO:0000269|PubMed:21533063}.
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase gamma
CC subunit family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC007591; AAD39660.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29304.1; -; Genomic_DNA.
DR EMBL; BT023415; AAY56406.1; -; mRNA.
DR EMBL; AK229160; BAF01033.1; -; mRNA.
DR EMBL; BT026513; ABH04620.1; -; mRNA.
DR PIR; F86287; F86287.
DR RefSeq; NP_172985.1; NM_101402.3.
DR AlphaFoldDB; Q9XI37; -.
DR SMR; Q9XI37; -.
DR STRING; 3702.AT1G15330.1; -.
DR PaxDb; Q9XI37; -.
DR PRIDE; Q9XI37; -.
DR ProteomicsDB; 224802; -.
DR EnsemblPlants; AT1G15330.1; AT1G15330.1; AT1G15330.
DR GeneID; 838102; -.
DR Gramene; AT1G15330.1; AT1G15330.1; AT1G15330.
DR KEGG; ath:AT1G15330; -.
DR Araport; AT1G15330; -.
DR TAIR; locus:2037853; AT1G15330.
DR eggNOG; KOG1764; Eukaryota.
DR HOGENOM; CLU_062724_0_0_1; -.
DR InParanoid; Q9XI37; -.
DR OMA; HAMNTLV; -.
DR OrthoDB; 1471847at2759; -.
DR PhylomeDB; Q9XI37; -.
DR PRO; PR:Q9XI37; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9XI37; baseline and differential.
DR Genevisible; Q9XI37; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0031588; C:nucleotide-activated protein kinase complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016208; F:AMP binding; IBA:GO_Central.
DR GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR GO; GO:0019887; F:protein kinase regulator activity; IBA:GO_Central.
DR GO; GO:0042149; P:cellular response to glucose starvation; IBA:GO_Central.
DR GO; GO:0003006; P:developmental process involved in reproduction; IMP:TAIR.
DR GO; GO:0009553; P:embryo sac development; IMP:UniProtKB.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0010183; P:pollen tube guidance; IMP:TAIR.
DR GO; GO:0006468; P:protein phosphorylation; IBA:GO_Central.
DR GO; GO:0050790; P:regulation of catalytic activity; IBA:GO_Central.
DR GO; GO:0048443; P:stamen development; IMP:UniProtKB.
DR Gene3D; 3.10.580.10; -; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR Pfam; PF00571; CBS; 1.
DR SMART; SM00116; CBS; 3.
DR SUPFAM; SSF54631; SSF54631; 2.
DR PROSITE; PS51371; CBS; 4.
PE 2: Evidence at transcript level;
KW CBS domain; Reference proteome; Repeat.
FT CHAIN 1..352
FT /note="SNF1-related protein kinase regulatory subunit
FT gamma-like PV42a"
FT /id="PRO_0000412193"
FT DOMAIN 24..106
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 122..196
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 210..281
FT /note="CBS 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 297..352
FT /note="CBS 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ SEQUENCE 352 AA; 38596 MW; 9F31877328EC512A CRC64;
MQEEKSKEDH SRLINVTAKD LTVRNRRLVE VPYTATLSHA MNTLVANSIS ALPVAAPPGH
WIGAGGSMIM ESDKQTGVVR KHYIGILTML DILAHIAGED SNLSDLDRKM SSQVSSIIGH
CLEGLSLWTL NPNTSVLECM EVFSKGIHRA LVPVESSIES NNTIAGVELI ESASAYKMLT
QMDLLRFLKD HHFDDLKTVL SRSISDLGAV NDSVYAITER TTVSNAINVM KGALLNAVPI
VHAPDIAQED HLQLVNGRHR KVIGTFSATD LKGCRLPELQ TWLPLTALEF TEKTSGKERE
VVSCGVESTM EEAIEKVVTR GVHRVWVMDQ QGLLQGVVSL TDIIRSLRST LS
