ID   PVAA_STRP6              Reviewed;         199 AA.
AC   Q5XC63;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Pneumococcal vaccine antigen A homolog;
GN   Name=pvaA; OrderedLocusNames=M6_Spy0865;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000250}.
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DR   EMBL; CP000003; AAT87000.1; -; Genomic_DNA.
DR   RefSeq; WP_011184512.1; NC_006086.1.
DR   AlphaFoldDB; Q5XC63; -.
DR   SMR; Q5XC63; -.
DR   CAZy; GH23; Glycoside Hydrolase Family 23.
DR   EnsemblBacteria; AAT87000; AAT87000; M6_Spy0865.
DR   KEGG; spa:M6_Spy0865; -.
DR   HOGENOM; CLU_101375_3_0_9; -.
DR   OMA; GNMFYAD; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..199
FT                   /note="Pneumococcal vaccine antigen A homolog"
FT                   /id="PRO_0000097113"
SQ   SEQUENCE   199 AA;  22105 MW;  8CBC37E15788F8A1 CRC64;
     MFRLLKRACS FLLFFVIYQS FVIHHNVQRV LAYKPMVEKT LAENDTKANV DLVLAMIYTE
     TKGGEADVMQ SSESSSGQKN SITDSQASIE HGVNLLSHNL ALAEEAGVDS WTAVQAYNFG
     TAYIDYIAKH GGQNTVDLAT TYSKTVVAPS LGNTSGQTYF YYHPLALISG GKLYKNGGNI
     YYSREVHFNL YLIELMSLF