ID   PVAA_STRP8              Reviewed;         199 AA.
AC   Q8P120;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Pneumococcal vaccine antigen A homolog;
GN   Name=pvaA; OrderedLocusNames=spyM18_1107;
OS   Streptococcus pyogenes serotype M18 (strain MGAS8232).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=186103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232;
RX   PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D.,
RA   Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A.,
RA   Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18 group
RT   A Streptococcus strains associated with acute rheumatic fever outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000250}.
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DR   EMBL; AE009949; AAL97729.1; -; Genomic_DNA.
DR   RefSeq; WP_002984653.1; NC_003485.1.
DR   AlphaFoldDB; Q8P120; -.
DR   SMR; Q8P120; -.
DR   CAZy; GH23; Glycoside Hydrolase Family 23.
DR   GeneID; 57852635; -.
DR   KEGG; spm:spyM18_1107; -.
DR   HOGENOM; CLU_101375_3_0_9; -.
DR   OMA; GNMFYAD; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..199
FT                   /note="Pneumococcal vaccine antigen A homolog"
FT                   /id="PRO_0000097114"
SQ   SEQUENCE   199 AA;  22071 MW;  8258DDE5B96C12A1 CRC64;
     MFRLLKRACS FLLLFVIYQS FVIHHNVQRV LAYKPMVEKT LAENDTKANV DLVLAMIYTE
     TKGGEADVMQ SSESSSGQKN SITDSQASIE HGVNLLSHNL ALAEEAGVDS WTAVQAYNFG
     TAYIDYIAKH GGQNTVDLAT TYSKTVVAPS LGNTSGQTYF YYHPLALISG GKLYKNGGNI
     YYSREVHFNL YLIELMSLF