PVA_PLAFA
ID PVA_PLAFA Reviewed; 224 AA.
AC P08116;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=Processed variable antigen;
DE Flags: Fragment;
OS Plasmodium falciparum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=3531849; DOI=10.1016/0166-6851(86)90107-6;
RA Coppel R.L., Culvenor J.G., Bianco A.E., Crewther P.E., Stahl H.-D.,
RA Brown G.V., Anders R.F., Kemp D.J.;
RT "Variable antigen associated with the surface of erythrocytes infected with
RT mature stages of Plasmodium falciparum.";
RL Mol. Biochem. Parasitol. 20:265-277(1986).
CC -!- MISCELLANEOUS: This variable antigen is associated with the surface of
CC erythrocytes infected with mature stages of plasmodium falciparum.
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DR EMBL; M15319; AAA29470.1; -; mRNA.
DR PIR; A45605; A45605.
DR AlphaFoldDB; P08116; -.
DR SMR; P08116; -.
DR VEuPathDB; PlasmoDB:PF3D7_0500800; -.
DR VEuPathDB; PlasmoDB:Pf7G8-2_000120300; -.
DR VEuPathDB; PlasmoDB:Pf7G8_050006300; -.
DR VEuPathDB; PlasmoDB:PfCD01_050007500; -.
DR VEuPathDB; PlasmoDB:PfDd2_050006000; -.
DR VEuPathDB; PlasmoDB:PfGA01_050005500; -.
DR VEuPathDB; PlasmoDB:PfGB4_050006200; -.
DR VEuPathDB; PlasmoDB:PfGN01_050005900; -.
DR VEuPathDB; PlasmoDB:PfHB3_050006000; -.
DR VEuPathDB; PlasmoDB:PfIT_050006200; -.
DR VEuPathDB; PlasmoDB:PfKE01_050005500; -.
DR VEuPathDB; PlasmoDB:PfKH01_050006500; -.
DR VEuPathDB; PlasmoDB:PfKH02_050006500; -.
DR VEuPathDB; PlasmoDB:PfML01_050005900; -.
DR VEuPathDB; PlasmoDB:PfNF135_050006600; -.
DR VEuPathDB; PlasmoDB:PfNF166_050006200; -.
DR VEuPathDB; PlasmoDB:PfNF54_050005500; -.
DR VEuPathDB; PlasmoDB:PfSD01_050006000; -.
DR VEuPathDB; PlasmoDB:PfSN01_050006300; -.
DR VEuPathDB; PlasmoDB:PfTG01_050006000; -.
PE 2: Evidence at transcript level;
KW Malaria; Repeat.
FT CHAIN <1..>224
FT /note="Processed variable antigen"
FT /id="PRO_0000217191"
FT REPEAT 1..6
FT /note="1"
FT REPEAT 7..12
FT /note="2"
FT REPEAT 13..18
FT /note="3"
FT REPEAT 19..24
FT /note="4"
FT REPEAT 25..30
FT /note="5"
FT REPEAT 31..36
FT /note="6"
FT REPEAT 37..42
FT /note="7"
FT REPEAT 43..48
FT /note="8"
FT REPEAT 49..54
FT /note="9"
FT REPEAT 55..60
FT /note="10"
FT REPEAT 61..66
FT /note="11"
FT REPEAT 67..72
FT /note="12"
FT REPEAT 73..78
FT /note="13"
FT REPEAT 79..84
FT /note="14"
FT REPEAT 85..90
FT /note="15"
FT REPEAT 91..96
FT /note="16"
FT REPEAT 97..102
FT /note="17"
FT REGION 1..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1..102
FT /note="17 X 6 AA tandem repeats of E-T-G-E-S-K"
FT COMPBIAS 1..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT NON_TER 224
SQ SEQUENCE 224 AA; 24749 MW; 12314AC48E8885CB CRC64;
ETGESKETGE SKETGESKET GESKETGESK ETGESKETGE SKETGESKET GESKETGESK
ETGESKETGE SKETGESKET GESKETGESK ETGESKETGE SKETRIYEET KYNKITSEFR
ETENVKITEE SKDREGNKVS GPYENSENSN VTSESEETKK LAEKEENEGE KLGENVNDGA
SENSEDPKKL TEQEENGTKE SSEETKDDKP EENEKKADNK KKKK
