ID   PVIP_NICBE              Reviewed;         549 AA.
AC   Q84N38;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=OBERON-like protein;
DE   AltName: Full=Potyvirus VPg-interacting protein;
DE            Short=PVIPnb;
GN   Name=PVIP;
OS   Nicotiana benthamiana.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4100;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH POTYVIRUS VPG PROTEIN.
RC   TISSUE=Leaf;
RX   PubMed=14963126; DOI=10.1128/jvi.78.5.2301-2309.2004;
RA   Dunoyer P., Thomas C., Harrison S., Revers F., Maule A.;
RT   "A cysteine-rich plant protein potentiates Potyvirus movement through an
RT   interaction with the virus genome-linked protein VPg.";
RL   J. Virol. 78:2301-2309(2004).
CC   -!- FUNCTION: Required for the maintenance and/or establishment of both the
CC       shoot and root meristems, probably by controlling the expression of the
CC       meristem genes and of genes required for auxin responses. Involved in
CC       the development of the basal pole and in auxin-mediated root and
CC       vascular development in the embryo (By similarity). Confers sensitivity
CC       to turnip mosaic virus (TuMV) probably by promoting viral movement and
CC       multiplication via interaction with TuMV VPg (Probable). {ECO:0000250,
CC       ECO:0000305}.
CC   -!- SUBUNIT: Self-interacts and probably forms heteromers (By similarity).
CC       Binds to VPg of pea seed borne mosaic virus (PSbMV), turnip mosaic
CC       virus (TuMV) and lettuce mosaic virus (LMV), but not with VPg of
CC       tobacco etch virus (TEV), cowpea mosaic virus (CPMV), tomato black ring
CC       virus (TBRV) and grapevine fan leaf virus (GFLV). {ECO:0000250,
CC       ECO:0000269|PubMed:14963126}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; AY271742; AAP22954.1; -; mRNA.
DR   AlphaFoldDB; Q84N38; -.
DR   SMR; Q84N38; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; ISS:UniProtKB.
DR   InterPro; IPR004082; OBERON.
DR   InterPro; IPR032535; Oberon_cc.
DR   InterPro; IPR032881; Oberon_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   PANTHER; PTHR21736; PTHR21736; 1.
DR   Pfam; PF16312; Oberon_cc; 1.
DR   Pfam; PF07227; PHD_Oberon; 1.
DR   PIRSF; PIRSF025218; DUF1423_pln; 1.
DR   PRINTS; PR01544; ARATH130DUF.
DR   SMART; SM00249; PHD; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Developmental protein; Host-virus interaction; Metal-binding;
KW   Nucleus; Zinc; Zinc-finger.
FT   CHAIN           1..549
FT                   /note="OBERON-like protein"
FT                   /id="PRO_0000399751"
FT   ZN_FING         224..288
FT                   /note="PHD-type"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          394..520
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        9..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        519..543
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   549 AA;  62233 MW;  A63AC23A0DA458B9 CRC64;
     MLPPRQQPRP GGLQTSLSLV SPDACGSPNP QERGSTSDQA RDSPSESASS RETWPTSDAL
     MLKKLEKEKE NGYTEHSVVR NISNSDKMSL RDIARERVDV IAERMRNLPD EYLEKFKHEL
     RVILEGLGGA QHREEFLFLQ RLVNSRGDLT DGTLIITHRT QLEILVAIKT GIQAFLHPSV
     SLSQASLIDI FLYKRCRNIA CGSMLPAEEC SCEICAKKNG FCNLCMCVIC YKFDFEVNSC
     RWIGCDLCSH WTHTDCAISN GQIGTGPSVK NGASSAETLF RCHACSRTSE LLGWVKDVFQ
     HCAPSWDAEA FVRELDYVRR IFQRSEDARG RKLFWKCEEL IEKLKNGVAD PMACKVILSF
     FQELDVDPSK SQDNDEGGRL IAPEEAFNKI ADVVQEAIRK MEAVAEEKMR MVKKARLALD
     ACDQELKDKA REVTSLKMER QRKKQQIDEL ESIVRLKQAE ADMFDLKAGE ARREAERLQR
     IALAKTEKSE EDYASRYLKQ RLSEAEAEKQ YLFEKIKLQE SSRASQSSAG GNDPSQMMYS
     KIQDLIKNM