ID   AAEA_ENT38              Reviewed;         310 AA.
AC   A4WF55;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeA {ECO:0000255|HAMAP-Rule:MF_01544};
DE            Short=pHBA efflux pump protein A {ECO:0000255|HAMAP-Rule:MF_01544};
GN   Name=aaeA {ECO:0000255|HAMAP-Rule:MF_01544}; OrderedLocusNames=Ent638_3678;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Forms an efflux pump with AaeB. {ECO:0000255|HAMAP-
CC       Rule:MF_01544}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01544}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01544}.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01544}.
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DR   EMBL; CP000653; ABP62335.1; -; Genomic_DNA.
DR   RefSeq; WP_015960658.1; NC_009436.1.
DR   AlphaFoldDB; A4WF55; -.
DR   SMR; A4WF55; -.
DR   STRING; 399742.Ent638_3678; -.
DR   EnsemblBacteria; ABP62335; ABP62335; Ent638_3678.
DR   KEGG; ent:Ent638_3678; -.
DR   eggNOG; COG1566; Bacteria.
DR   HOGENOM; CLU_018816_15_2_6; -.
DR   OMA; EVEPTFN; -.
DR   OrthoDB; 757027at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01544; AaeA; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   InterPro; IPR022871; PHBA_efflux_pump_AaeA.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   TIGRFAMs; TIGR01730; RND_mfp; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..310
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeA"
FT                   /id="PRO_1000068804"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01544"
SQ   SEQUENCE   310 AA;  34552 MW;  9568C40D7003E80E CRC64;
     MKTLTRNISR TAITVALVIL AFIAISRAWV FYTESPWTRD ARFSADIVAI APDVAGLITA
     VNVRDNQLVK KDQVLFTIDQ PRYQKALEES EADVAYYQAL TTEKRREAGR RNKLGIQAMS
     REEIDQSNNL LQTVLHQLAK AEATRDLAKL DLERTVIRAP SDGWVTNLNV YTGEFITRGS
     TAVALVKQHS FYVLAYMEET KLEGVRPGYR AEITPLGSNR VLKGTVDSIA AGVTNSSATR
     DSKGMATVDS NLEWVRLAQR VPVRIRLDDE QGNLWPAGTT ATVVITGEKD RNASNDSLFR
     KIAHRLREFG