ID   ATP6_SALTR              Reviewed;         105 AA.
AC   Q36967; Q35938;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=ATP synthase subunit a;
DE   AltName: Full=F-ATPase protein 6;
DE   Flags: Fragment;
GN   Name=mt-atp6; Synonyms=atp6, atpase6, mtatp6;
OS   Salmo trutta (Brown trout).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8032;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7912616; DOI=10.1111/j.1365-294x.1994.tb00117.x;
RA   Giuffra E., Bernatchez L., Guyomard R.;
RT   "Mitochondrial control region and protein coding genes sequence variation
RT   among phenotypic forms of brown trout Salmo trutta from northern Italy.";
RL   Mol. Ecol. 3:161-171(1994).
CC   -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or
CC       Complex V) produces ATP from ADP in the presence of a proton gradient
CC       across the membrane which is generated by electron transport complexes
CC       of the respiratory chain. F-type ATPases consist of two structural
CC       domains, F(1) - containing the extramembraneous catalytic core and F(0)
CC       - containing the membrane proton channel, linked together by a central
CC       stalk and a peripheral stalk. During catalysis, ATP synthesis in the
CC       catalytic domain of F(1) is coupled via a rotary mechanism of the
CC       central stalk subunits to proton translocation. Key component of the
CC       proton channel; it may play a direct role in the translocation of
CC       protons across the membrane.
CC   -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC       - and CF(0) - the membrane proton channel. CF(1) has five subunits:
CC       alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main
CC       subunits: a, b and c.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the ATPase A chain family. {ECO:0000305}.
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DR   EMBL; X74240; CAA52302.1; -; Genomic_DNA.
DR   EMBL; X74241; CAA52303.1; -; Genomic_DNA.
DR   EMBL; X74242; CAA52304.1; -; Genomic_DNA.
DR   EMBL; X74243; CAA52305.1; -; Genomic_DNA.
DR   EMBL; X74244; CAA52306.1; -; Genomic_DNA.
DR   EMBL; X74245; CAA52307.1; -; Genomic_DNA.
DR   PIR; S36396; S36396.
DR   AlphaFoldDB; Q36967; -.
DR   SMR; Q36967; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015986; P:proton motive force-driven ATP synthesis; IEA:InterPro.
DR   Gene3D; 1.20.120.220; -; 1.
DR   InterPro; IPR000568; ATP_synth_F0_asu.
DR   InterPro; IPR023011; ATP_synth_F0_asu_AS.
DR   InterPro; IPR045083; ATP_synth_F0_asu_bact/mt.
DR   InterPro; IPR035908; F0_ATP_A_sf.
DR   PANTHER; PTHR11410; PTHR11410; 1.
DR   Pfam; PF00119; ATP-synt_A; 1.
DR   PRINTS; PR00123; ATPASEA.
DR   SUPFAM; SSF81336; SSF81336; 1.
DR   TIGRFAMs; TIGR01131; ATP_synt_6_or_A; 1.
DR   PROSITE; PS00449; ATPASE_A; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; CF(0); Hydrogen ion transport; Ion transport; Membrane;
KW   Mitochondrion; Mitochondrion inner membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           <1..>105
FT                   /note="ATP synthase subunit a"
FT                   /id="PRO_0000082168"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VARIANT         26
FT                   /note="I -> V (in haplotypes MA)"
FT   NON_TER         1
FT   NON_TER         105
SQ   SEQUENCE   105 AA;  11291 MW;  909F660F959318A3 CRC64;
     RNQPTAALGH LLPEGTPVPL IPVLIIIETI SLFIRPLALG VRLTANLTAG HLLIQLIATA
     AFVLLPMMPT VAILTSIVLF LLTLLEIAVA MIQAYVFVLL LSLYL