ID   PX11B_BOVIN             Reviewed;         258 AA.
AC   Q148K5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Peroxisomal membrane protein 11B;
DE   AltName: Full=Peroxin-11B;
DE   AltName: Full=Peroxisomal biogenesis factor 11B;
GN   Name=PEX11B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in peroxisomal proliferation. May regulate
CC       peroxisome division by recruiting the dynamin-related GTPase DNM1L to
CC       the peroxisomal membrane. Promotes membrane protrusion and elongation
CC       on the peroxisomal surface. {ECO:0000250|UniProtKB:O96011}.
CC   -!- SUBUNIT: Homodimer. Heterodimer with PEX11G. Interacts with PEX19.
CC       Interacts with FIS1. {ECO:0000250|UniProtKB:O96011}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC       {ECO:0000250|UniProtKB:O96011}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:O96011}.
CC   -!- SIMILARITY: Belongs to the peroxin-11 family. {ECO:0000305}.
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DR   EMBL; BC118195; AAI18196.1; -; mRNA.
DR   RefSeq; NP_001068734.1; NM_001075266.1.
DR   AlphaFoldDB; Q148K5; -.
DR   SMR; Q148K5; -.
DR   STRING; 9913.ENSBTAP00000011022; -.
DR   PaxDb; Q148K5; -.
DR   PRIDE; Q148K5; -.
DR   Ensembl; ENSBTAT00000011022; ENSBTAP00000011022; ENSBTAG00000008372.
DR   GeneID; 506527; -.
DR   KEGG; bta:506527; -.
DR   CTD; 8799; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008372; -.
DR   VGNC; VGNC:32752; PEX11B.
DR   eggNOG; KOG4186; Eukaryota.
DR   GeneTree; ENSGT00390000014273; -.
DR   HOGENOM; CLU_049216_2_0_1; -.
DR   InParanoid; Q148K5; -.
DR   OMA; RFWAMGL; -.
DR   OrthoDB; 1394894at2759; -.
DR   TreeFam; TF325704; -.
DR   Reactome; R-BTA-9603798; Class I peroxisomal membrane protein import.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000008372; Expressed in choroid plexus and 104 other tissues.
DR   GO; GO:0005779; C:integral component of peroxisomal membrane; IEA:Ensembl.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0016559; P:peroxisome fission; IBA:GO_Central.
DR   GO; GO:0044375; P:regulation of peroxisome size; IBA:GO_Central.
DR   InterPro; IPR008733; PEX11.
DR   Pfam; PF05648; PEX11; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Membrane; Peroxisome; Peroxisome biogenesis;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..258
FT                   /note="Peroxisomal membrane protein 11B"
FT                   /id="PRO_0000330308"
FT   TRANSMEM        232..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          210..258
FT                   /note="Interaction with PEX19, PEX11G and FIS1 and
FT                   peroxisome targeting"
FT                   /evidence="ECO:0000250|UniProtKB:O96011"
FT   MOD_RES         43
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:O96011"
SQ   SEQUENCE   258 AA;  28278 MW;  57D9625E6F23EDAF CRC64;
     MDAWVRFSAQ SQARERLCRA AQYACSLLGH ALQKHGASPE LQKQIRQLEG HLSLGRKLLR
     LGNSADALES AKRAVHLSDV VLRFCITVSH LNRALYFACD NVLWAGKSGL APRVDQEKWA
     QRSFRYYLFS LIMNLSRDAY EIRLLMEQES SACSRRLKGS GGVSGGIEPG GPGGPGIPGG
     GLPQVALKLR LRVLLLARVL RGHPPLLLDV VRNACDLFIP LDKLGLWRCG PGIVGLCGLV
     SSILSILTLI CPWLRLKP