ID   PX11B_PONAB             Reviewed;         259 AA.
AC   Q5RFI0;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Peroxisomal membrane protein 11B;
DE   AltName: Full=Peroxin-11B;
DE   AltName: Full=Peroxisomal biogenesis factor 11B;
DE   AltName: Full=Protein PEX11 homolog beta;
DE            Short=PEX11-beta;
GN   Name=PEX11B;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in peroxisomal proliferation. May regulate
CC       peroxisome division by recruiting the dynamin-related GTPase DNM1L to
CC       the peroxisomal membrane. Promotes membrane protrusion and elongation
CC       on the peroxisomal surface. {ECO:0000250|UniProtKB:O96011}.
CC   -!- SUBUNIT: Homodimer. Heterodimer with PEX11G. Interacts with PEX19.
CC       Interacts with FIS1. {ECO:0000250|UniProtKB:O96011}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC       {ECO:0000250|UniProtKB:O96011}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:O96011}.
CC   -!- SIMILARITY: Belongs to the peroxin-11 family. {ECO:0000305}.
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DR   EMBL; CR857177; CAH89477.1; -; mRNA.
DR   RefSeq; NP_001127153.1; NM_001133681.2.
DR   AlphaFoldDB; Q5RFI0; -.
DR   SMR; Q5RFI0; -.
DR   STRING; 9601.ENSPPYP00000001084; -.
DR   PRIDE; Q5RFI0; -.
DR   GeneID; 100174204; -.
DR   KEGG; pon:100174204; -.
DR   CTD; 8799; -.
DR   eggNOG; KOG4186; Eukaryota.
DR   InParanoid; Q5RFI0; -.
DR   OrthoDB; 1394894at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005779; C:integral component of peroxisomal membrane; ISS:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
DR   InterPro; IPR008733; PEX11.
DR   Pfam; PF05648; PEX11; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Membrane; Peroxisome; Peroxisome biogenesis;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..259
FT                   /note="Peroxisomal membrane protein 11B"
FT                   /id="PRO_0000105969"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          211..259
FT                   /note="Interaction with PEX19, PEX11G and FIS1 and
FT                   peroxisome targeting"
FT                   /evidence="ECO:0000250|UniProtKB:O96011"
FT   MOD_RES         43
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:O96011"
SQ   SEQUENCE   259 AA;  28539 MW;  7735C9D0C6C636EA CRC64;
     MDAWVRFSAQ SQARERLCRA AQYACSLLGH VLQRHGASPE LQKQIRQLES HLSLGRKLLR
     LGNSADALES AKRAVHLSDV VLRFCITVSH LNRALYFACD NVLWAGKSGL APRVDQEKWA
     QRSFRYYLFS LIMNLSRDAY EIRLLMEQES SACSRRLKGS GGGVPGGSET GGLGGPGTPG
     GHLPQLALKL RLQVLLLARV LRGHPPLLLD VVRNACDLFI PLDKLGLWRC GPGIVGLCGL
     VSSILSILTL IYPWLRLKP