ID   PX24A_DICDI             Reviewed;         202 AA.
AC   Q54ZX5; Q86K50;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=PXMP2/4 family protein 1;
GN   ORFNames=DDB_G0277335;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL68854.1; -; Genomic_DNA.
DR   RefSeq; XP_642741.1; XM_637649.1.
DR   AlphaFoldDB; Q54ZX5; -.
DR   STRING; 44689.DDB0302422; -.
DR   PaxDb; Q54ZX5; -.
DR   EnsemblProtists; EAL68854; EAL68854; DDB_G0277335.
DR   GeneID; 8620934; -.
DR   KEGG; ddi:DDB_G0277335; -.
DR   dictyBase; DDB_G0277335; -.
DR   eggNOG; KOG1944; Eukaryota.
DR   HOGENOM; CLU_049109_8_2_1; -.
DR   InParanoid; Q54ZX5; -.
DR   OMA; WNCILST; -.
DR   PhylomeDB; Q54ZX5; -.
DR   Reactome; R-DDI-9603798; Class I peroxisomal membrane protein import.
DR   PRO; PR:Q54ZX5; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PTHR11266; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..202
FT                   /note="PXMP2/4 family protein 1"
FT                   /id="PRO_0000333833"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   202 AA;  23393 MW;  1E84503B02FD1279 CRC64;
     MNFRIFDKIG NSYKKSLQNR PVITKSLTGT VVFFLGDTLA QKIENRGYDP KRTLMMCTVG
     TFIVVPQIHF WFKFLDKTFT KPGWAGAIPK VVVDQLTFGP YLFVCNMTSV QLFHQGFNFD
     THQWKDKMKK DFFPVLQKAW MIWPLTNCIL FRFVHPDYRI LISNLVSVGW NCILSTVSNK
     SFLKNNNNNN DPSISTMASL NE