ID   PX24B_DICDI             Reviewed;         193 AA.
AC   Q54XX9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=PXMP2/4 family protein 2;
GN   ORFNames=DDB_G0278529;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68437.1; -; Genomic_DNA.
DR   RefSeq; XP_642423.1; XM_637331.1.
DR   AlphaFoldDB; Q54XX9; -.
DR   PaxDb; Q54XX9; -.
DR   PRIDE; Q54XX9; -.
DR   EnsemblProtists; EAL68437; EAL68437; DDB_G0278529.
DR   GeneID; 8621628; -.
DR   KEGG; ddi:DDB_G0278529; -.
DR   dictyBase; DDB_G0278529; -.
DR   eggNOG; KOG1944; Eukaryota.
DR   HOGENOM; CLU_049109_8_2_1; -.
DR   InParanoid; Q54XX9; -.
DR   OMA; KGWEDFE; -.
DR   PhylomeDB; Q54XX9; -.
DR   Reactome; R-DDI-9033241; Peroxisomal protein import.
DR   PRO; PR:Q54XX9; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PTHR11266; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..193
FT                   /note="PXMP2/4 family protein 2"
FT                   /id="PRO_0000333834"
FT   TRANSMEM        56..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   193 AA;  22362 MW;  314472D7B57BFFA2 CRC64;
     MRKLWGLYLG LLDNHPLVTK SLSTGFLMGT GDILAQRLEH KFKDEKSQFK LDYKRVATMS
     TVGIFYSGPM LHYWYRSLDI MVKGEGRSVI IKKMLIDQLL FAPVAIGGFM TVTNFINNKG
     ELKNLENFTK ELFYAVKINW LIWPAAQIIN FSLVPPNLRV LYSSIISIFW GMFLSHISFD
     KDHHIRNQNK EIN