ID   PX24C_DICDI             Reviewed;         184 AA.
AC   Q54GD8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=PXMP2/4 family protein 3;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0290223;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000161; EAL62333.1; -; Genomic_DNA.
DR   RefSeq; XP_635840.1; XM_630748.1.
DR   AlphaFoldDB; Q54GD8; -.
DR   STRING; 44689.DDB0302425; -.
DR   PaxDb; Q54GD8; -.
DR   EnsemblProtists; EAL62333; EAL62333; DDB_G0290223.
DR   GeneID; 8627548; -.
DR   KEGG; ddi:DDB_G0290223; -.
DR   dictyBase; DDB_G0290223; -.
DR   eggNOG; KOG1944; Eukaryota.
DR   HOGENOM; CLU_049109_9_0_1; -.
DR   InParanoid; Q54GD8; -.
DR   OMA; RWGTYDW; -.
DR   PhylomeDB; Q54GD8; -.
DR   PRO; PR:Q54GD8; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PTHR11266; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..44
FT                   /evidence="ECO:0000255"
FT   CHAIN           45..184
FT                   /note="PXMP2/4 family protein 3"
FT                   /id="PRO_0000333835"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   184 AA;  21260 MW;  B61F80F9F6CAB4A4 CRC64;
     MSNSKPLSLT DAVTTWYMKK LKSKPIQTKA LTSATLSFIS SVVAQKFIEK KKINWNAVVK
     FTVWGLISSP LVHYWHIILD RLFKNIKDKY QSWGKLIVDQ LVFAPFINIA FYSVLAILDG
     KPKSILFKLY FDLFPTLKAS WKVWPLAQLI NFRFVPSHLR VLFGNLVGFC WGIYLSILAT
     KKRN