ID   PXDC2_XENLA             Reviewed;         513 AA.
AC   Q6DE92;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Plexin domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=plxdc2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the plexin family. {ECO:0000305}.
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DR   EMBL; BC077242; AAH77242.1; -; mRNA.
DR   RefSeq; NP_001086655.1; NM_001093186.1.
DR   AlphaFoldDB; Q6DE92; -.
DR   SMR; Q6DE92; -.
DR   DNASU; 446490; -.
DR   GeneID; 446490; -.
DR   KEGG; xla:446490; -.
DR   CTD; 446490; -.
DR   Xenbase; XB-GENE-856534; plxdc2.S.
DR   OrthoDB; 1361987at2759; -.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 446490; Expressed in ovary and 16 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR031152; PLXDC.
DR   InterPro; IPR031154; PLXDC2.
DR   InterPro; IPR016201; PSI.
DR   PANTHER; PTHR13055; PTHR13055; 1.
DR   PANTHER; PTHR13055:SF11; PTHR13055:SF11; 1.
DR   Pfam; PF01437; PSI; 1.
DR   SMART; SM00423; PSI; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..513
FT                   /note="Plexin domain-containing protein 2"
FT                   /id="PRO_0000234576"
FT   TOPO_DOM        25..438
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        460..513
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          312..357
FT                   /note="PSI"
FT   CARBOHYD        88
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        145
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        198
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        206
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        222
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        330
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   513 AA;  57622 MW;  301EA53F2905A4ED CRC64;
     MGARSESLVG VVLLFQLLAD RLWCAATASD SLYDVSYSIT AIKPRVDEMV SVDTHMYSHR
     WKRQSVDTNR PSVGQDFPDM FLEGTNENGT EIEEDTDHKY YTSRTYGPLD SASRDLWVNI
     DQMEKEKVKI HGILSNTHRQ AARVNLSFDF PFYGHFLREI TVATGGFIYT GEVVHRMLTA
     TQYIAPLMAN FDPSVSRNST VRYFDNGTAL VVQWDHVHLR DNYSLGSFTF QATLINDGRI
     VFGYKDIPVP VMQISSTNHP VKVGLSDAFV VVHKIQQIPN VRRRTIFEYH RVELEMTKIT
     SFSAVEMLPL ATCLQFNSCS SCVSSMIGFN CSWCNIPQRC SSGFDRHRQD WVENGCTEES
     KDTVCDDLLQ TTGISHHTTT GLHATTSIYA FTTTTRMASH FPSNLPTEDD TKIALHLKDN
     GASTDNSAAE MKTGTLHTGL IIGILILVLL IITAILVAVY MYHHPTSSAS LFLIERRPSR
     WPAMKFRRGS GHPAYAEVEP IGEKEGFIVS EQC