PXL2C_ARATH
ID PXL2C_ARATH Reviewed; 248 AA.
AC Q9ZUU2; Q94A62;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Thioredoxin-like protein AAED1, chloroplastic;
DE AltName: Full=AhpC/TSA antioxidant enzyme domain-containing protein 1;
DE Flags: Precursor;
GN OrderedLocusNames=At2g37240; ORFNames=F3G5.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-53, CLEAVAGE OF TRANSIT PEPTIDE
RP [LARGE SCALE ANALYSIS] AFTER SER-52, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the peroxiredoxin-like PRXL2 family. PRXL2C
CC subfamily. {ECO:0000305}.
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DR EMBL; AC005896; AAC98045.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC09371.1; -; Genomic_DNA.
DR EMBL; AY050345; AAK91362.1; -; mRNA.
DR EMBL; BT006337; AAP21145.1; -; mRNA.
DR EMBL; AY088891; AAM67197.1; -; mRNA.
DR PIR; C84790; C84790.
DR RefSeq; NP_030274.1; NM_129280.3.
DR AlphaFoldDB; Q9ZUU2; -.
DR STRING; 3702.AT2G37240.1; -.
DR iPTMnet; Q9ZUU2; -.
DR PaxDb; Q9ZUU2; -.
DR PRIDE; Q9ZUU2; -.
DR ProteomicsDB; 226025; -.
DR EnsemblPlants; AT2G37240.1; AT2G37240.1; AT2G37240.
DR GeneID; 818301; -.
DR Gramene; AT2G37240.1; AT2G37240.1; AT2G37240.
DR KEGG; ath:AT2G37240; -.
DR Araport; AT2G37240; -.
DR TAIR; locus:2049801; AT2G37240.
DR eggNOG; KOG4498; Eukaryota.
DR HOGENOM; CLU_075681_0_0_1; -.
DR InParanoid; Q9ZUU2; -.
DR OMA; DMDDVLK; -.
DR OrthoDB; 1255928at2759; -.
DR PhylomeDB; Q9ZUU2; -.
DR PRO; PR:Q9ZUU2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUU2; baseline and differential.
DR Genevisible; Q9ZUU2; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0016209; F:antioxidant activity; IBA:GO_Central.
DR InterPro; IPR032801; PXL2A/B/C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR28630; PTHR28630; 1.
DR Pfam; PF13911; AhpC-TSA_2; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
PE 1: Evidence at protein level;
KW Acetylation; Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..52
FT /note="Chloroplast"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 53..248
FT /note="Thioredoxin-like protein AAED1, chloroplastic"
FT /id="PRO_0000036275"
FT MOD_RES 53
FT /note="N-acetylalanine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 248 AA; 26605 MW; A4F33DB15DACD094 CRC64;
MAIALSSSST ITSITLQPKL KTIHGLGTVL PGYSVKSHFR SVSLRRSAVV VSAITGASSG
AGIGKGTADS LDTVKVLDLR GNEIPISDLW KDRKAVVAFA RHFGCVLCRK RAAYLAEKKD
VMDASGVALV LIGPGSIDQA NTFVEQTKFK GEVYADPNHA SYEALEFVSG VSVTFTPKAA
MKILESYMEG YRQDWKLSFM KDTVERGGWQ QGGILVAGPG KDNISYIRKD KEAGDDPPVE
EILKACCA
