ID   PXPB_ECO57              Reviewed;         218 AA.
AC   P0AAV5; P75744;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=5-oxoprolinase subunit B {ECO:0000250|UniProtKB:P0AAV4};
DE            Short=5-OPase subunit B {ECO:0000250|UniProtKB:P0AAV4};
DE            EC=3.5.2.9 {ECO:0000250|UniProtKB:P0AAV4};
DE   AltName: Full=5-oxoprolinase (ATP-hydrolyzing) subunit B {ECO:0000250|UniProtKB:P0AAV4};
GN   Name=pxpB {ECO:0000250|UniProtKB:P0AAV4}; Synonyms=ybgJ;
GN   OrderedLocusNames=Z0862, ECs0736;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Catalyzes the cleavage of 5-oxoproline to form L-glutamate
CC       coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
CC       {ECO:0000250|UniProtKB:P0AAV4}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate +
CC         phosphate; Xref=Rhea:RHEA:10348, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58402, ChEBI:CHEBI:456216; EC=3.5.2.9;
CC         Evidence={ECO:0000250|UniProtKB:P0AAV4};
CC   -!- SUBUNIT: Forms a complex composed of PxpA, PxpB and PxpC.
CC       {ECO:0000250|UniProtKB:P60495}.
CC   -!- SIMILARITY: Belongs to the PxpB family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG55034.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34159.1; -; Genomic_DNA.
DR   PIR; F85571; F85571.
DR   PIR; H90720; H90720.
DR   RefSeq; NP_308763.1; NC_002695.1.
DR   RefSeq; WP_001188343.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AAV5; -.
DR   SMR; P0AAV5; -.
DR   STRING; 155864.EDL933_0777; -.
DR   EnsemblBacteria; AAG55034; AAG55034; Z0862.
DR   EnsemblBacteria; BAB34159; BAB34159; ECs_0736.
DR   GeneID; 66671020; -.
DR   GeneID; 917105; -.
DR   KEGG; ece:Z0862; -.
DR   KEGG; ecs:ECs_0736; -.
DR   PATRIC; fig|386585.9.peg.852; -.
DR   eggNOG; COG2049; Bacteria.
DR   HOGENOM; CLU_020207_0_0_6; -.
DR   OMA; QPGFAYM; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.100.10; -; 1.
DR   InterPro; IPR003833; CT_C_D.
DR   InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR   InterPro; IPR010016; KipI_fam.
DR   PANTHER; PTHR34698; PTHR34698; 1.
DR   Pfam; PF02682; CT_C_D; 1.
DR   SMART; SM00796; AHS1; 1.
DR   SUPFAM; SSF50891; SSF50891; 1.
DR   TIGRFAMs; TIGR00370; TIGR00370; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..218
FT                   /note="5-oxoprolinase subunit B"
FT                   /id="PRO_0000168707"
SQ   SEQUENCE   218 AA;  23947 MW;  6AEBA50408732890 CRC64;
     MQRARCYLIG ETAVVLELEP PVTLASQKRI WRLAQRLVDM PNVVEAIPGM NNITVILRNP
     ESLALDAIER LQRWWEESEA LEPESRFIEI PVVYGGAGGP DLAVVAAHCG LSEKQVVELH
     SSVEYVVWFL GFQPGFPYLG SLPEQLHTPR RAEPRLLVPA GSVGIGGPQT GVYPLATPGG
     WQLIGHTSLS LFDPARDEPI LLRPGDSVRF VPQKEGVC