ID   PXR1_ASPCL              Reviewed;         291 AA.
AC   A1CD56;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Protein pxr1;
DE   AltName: Full=PinX1-related protein 1;
GN   Name=pxr1; ORFNames=ACLA_005360;
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Involved in rRNA-processing at A0, A1 and A2 sites and
CC       regulates negatively telomerase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PINX1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAW11783.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS027051; EAW11783.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001273209.1; XM_001273208.1.
DR   AlphaFoldDB; A1CD56; -.
DR   STRING; 5057.CADACLAP00000709; -.
DR   PRIDE; A1CD56; -.
DR   GeneID; 4705616; -.
DR   KEGG; act:ACLA_005360; -.
DR   eggNOG; KOG2809; Eukaryota.
DR   OrthoDB; 1577610at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR000467; G_patch_dom.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..291
FT                   /note="Protein pxr1"
FT                   /id="PRO_0000324878"
FT   DOMAIN          25..79
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          146..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..160
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..263
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  32778 MW;  4BF4CCFBB44B38A2 CRC64;
     MGLAAPRKRT KISHDPNNTT WSRSTDGFGH RILKAQGWTP GSFLGPRNAA HSDLFTTASA
     SHIRVVLKDD NLGLGARPKR GLLDEPTGLD AFKGLLGRLN GKSETQLVVE QQKRDDIKLA
     RYAAAKWQAV RFVSGGLLVQ ESNETLVPPT SQNGQADSEV KNVPQGREEG LADDETTNSD
     SEDRHSVEKR KKKETNSRGS REKERKREKR QMRRDKKRKT SESTESEAEM QEKTRVQGPS
     EDVKPTEPKA PTLSRERRPM GRQMFRGRYI AQKKRALMDD KSLNEIFMIS T