PXR1_ASPNC
ID PXR1_ASPNC Reviewed; 285 AA.
AC A2R156;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Protein pxr1;
DE AltName: Full=PinX1-related protein 1;
GN Name=pxr1; ORFNames=An13g00030;
OS Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- FUNCTION: Involved in rRNA-processing at A0, A1 and A2 sites and
CC regulates negatively telomerase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PINX1 family. {ECO:0000305}.
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DR EMBL; AM270295; CAK46406.1; -; Genomic_DNA.
DR RefSeq; XP_001396145.1; XM_001396108.1.
DR AlphaFoldDB; A2R156; -.
DR PaxDb; A2R156; -.
DR PRIDE; A2R156; -.
DR EnsemblFungi; CAK46406; CAK46406; An13g00030.
DR GeneID; 4986469; -.
DR KEGG; ang:ANI_1_512114; -.
DR VEuPathDB; FungiDB:An13g00030; -.
DR HOGENOM; CLU_052839_0_0_1; -.
DR Proteomes; UP000006706; Chromosome 2L.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR000467; G_patch_dom.
DR Pfam; PF01585; G-patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..285
FT /note="Protein pxr1"
FT /id="PRO_0000324880"
FT DOMAIN 25..79
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 31334 MW; EB1240ECC16E361C CRC64;
MGLAAPRKKI KISHDPNNTN WSRSTSGFGH KILSSQGWTP GSFLGARNAA HAEMFTAASA
SHIKVVLKDD TLGLGARPKR DPLNEPTGLD AFKGLLGRLN GKSDADLQVE QQKRDNVKLA
RYAATKWQAV TFISGGLLAQ EKTTPIVTEE PQGIHKDKQE DKLSATVPGP DSDGVEGSDN
IGGQSDQSIK KKKSKSKNHR EKKDRKRKHT EEPESTDSGN TNKRSTEKKS KATRDDEESS
STTSKGLSRE RRPMGRHVFR GRHIAQKKAA LMDEKSLNEI FMVKS
