ID   PXR1_MAGO7              Reviewed;         346 AA.
AC   A4R0T9; G4MQM5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Protein PXR1;
DE   AltName: Full=PinX1-related protein 1;
GN   Name=PXR1; ORFNames=MGG_09279;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Involved in rRNA-processing at A0, A1 and A2 sites and
CC       regulates negatively telomerase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PINX1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM001231; EHA57312.1; -; Genomic_DNA.
DR   RefSeq; XP_003709924.1; XM_003709876.1.
DR   AlphaFoldDB; A4R0T9; -.
DR   STRING; 318829.MGG_16274T0; -.
DR   PRIDE; A4R0T9; -.
DR   EnsemblFungi; MGG_16274T0; MGG_16274T0; MGG_16274.
DR   GeneID; 12985297; -.
DR   KEGG; mgr:MGG_16274; -.
DR   VEuPathDB; FungiDB:MGG_16274; -.
DR   eggNOG; KOG2809; Eukaryota.
DR   HOGENOM; CLU_052839_0_0_1; -.
DR   InParanoid; A4R0T9; -.
DR   OMA; WDQSSEA; -.
DR   OrthoDB; 1577610at2759; -.
DR   Proteomes; UP000009058; Chromosome 1.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR000467; G_patch_dom.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..346
FT                   /note="Protein PXR1"
FT                   /id="PRO_0000324891"
FT   DOMAIN          25..79
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          146..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..186
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..217
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..270
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        286..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   346 AA;  39026 MW;  841EA84321733A5E CRC64;
     MGLAAPKNKR KLGNDPNNTR WSRNTENFGH RMLRSQGWEP GQYLGPQDAS HAVYHTAASA
     SHIKVALKED NLGLGAKMNR GDECTGLNAF KEMLARLNGK SEAAIEKDKK AREAHAMNVY
     VERKFGTMRF VSGGFLVGDV IQEKKEDAEA ESTDGTPEPA EATVKKEKKR KAGRDDDDEA
     QSKEERRRAK KQKKSMKETG SGGDDVTSEE DSAKSKSKKS HKSKKEKKRR KEEPASDEQE
     SEDEESREKR RKKEKKERKE RRREKREKKL KKKQQREEDS SSSEANSDDE TTGVDTGAST
     PVASGTSTPV SQVSVRHLAR RRFIAQKRMA MKDQQALNQI FMIKSS