PYHD_CPVBM
ID PYHD_CPVBM Reviewed; 248 AA.
AC P11041;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 02-JUN-2021, entry version 83.
DE RecName: Full=Polyhedrin;
DE AltName: Full=C-polyhedrin;
DE Flags: Precursor;
OS Bombyx mori cytoplasmic polyhedrosis virus (BmCPV).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Spinareovirinae; Cypovirus.
OX NCBI_TaxID=110829;
OH NCBI_TaxID=7091; Bombyx mori (Silk moth).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=H;
RX PubMed=3275433; DOI=10.1128/jvi.62.1.211-217.1988;
RA Arella M., Lavallee C., Belloncik S., Furuichi Y.;
RT "Molecular cloning and characterization of cytoplasmic polyhedrosis virus
RT polyhedrin and a viable deletion mutant gene.";
RL J. Virol. 62:211-217(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=A, and H;
RX PubMed=2661724; DOI=10.1099/0022-1317-70-7-1885;
RA Mori H., Minobe Y., Sasaki T., Kawase S.;
RT "Nucleotide sequence of the polyhedrin gene of Bombyx mori cytoplasmic
RT polyhedrosis virus A strain with nuclear localization of polyhedra.";
RL J. Gen. Virol. 70:1885-1888(1989).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=A;
RA Mori H.;
RL Submitted (JUL-1994) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Major component of the virus occlusion bodies, which are
CC large proteinaceous structures (polyhedra), that protect the virus from
CC the outside environment for extended periods until they are ingested by
CC insect larvae.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm. Note=Strain H polyhedrin is found
CC in the cytoplasm, while strain A is found in the nucleus.
CC -!- MISCELLANEOUS: The sequence of strain H is shown.
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DR EMBL; M19112; AAA46694.1; -; Genomic_RNA.
DR EMBL; D37768; BAA07022.1; -; Genomic_RNA.
DR PIR; A29961; PYXRCP.
DR PDB; 5A9B; X-ray; 1.88 A; A=1-70, A=104-248.
DR PDB; 5AXU; X-ray; 1.60 A; A=2-248.
DR PDB; 5AXV; X-ray; 2.04 A; A=2-248.
DR PDB; 5EXY; X-ray; 1.55 A; A=2-248.
DR PDB; 5EXZ; X-ray; 1.90 A; A=2-248.
DR PDB; 5GQI; X-ray; 1.30 A; A=2-248.
DR PDB; 5GQJ; X-ray; 1.50 A; A=2-248.
DR PDB; 5GQK; X-ray; 1.50 A; A=2-248.
DR PDB; 5GQL; X-ray; 1.78 A; A=2-248.
DR PDB; 5GQM; X-ray; 1.68 A; A=2-248.
DR PDB; 5GQN; X-ray; 1.55 A; A=2-248.
DR PDB; 5YHA; X-ray; 1.58 A; A=2-248.
DR PDB; 5YHB; X-ray; 2.08 A; A=2-248.
DR PDB; 5YR1; X-ray; 1.72 A; A=1-248.
DR PDB; 5YR9; X-ray; 1.70 A; A=1-248.
DR PDB; 5YRA; X-ray; 1.79 A; A=1-248.
DR PDB; 5YRB; X-ray; 1.65 A; A=1-248.
DR PDB; 5YRC; X-ray; 1.67 A; A=1-248.
DR PDB; 5YRD; X-ray; 1.85 A; A=1-248.
DR PDB; 6LEE; X-ray; 1.95 A; A=2-248.
DR PDBsum; 5A9B; -.
DR PDBsum; 5AXU; -.
DR PDBsum; 5AXV; -.
DR PDBsum; 5EXY; -.
DR PDBsum; 5EXZ; -.
DR PDBsum; 5GQI; -.
DR PDBsum; 5GQJ; -.
DR PDBsum; 5GQK; -.
DR PDBsum; 5GQL; -.
DR PDBsum; 5GQM; -.
DR PDBsum; 5GQN; -.
DR PDBsum; 5YHA; -.
DR PDBsum; 5YHB; -.
DR PDBsum; 5YR1; -.
DR PDBsum; 5YR9; -.
DR PDBsum; 5YRA; -.
DR PDBsum; 5YRB; -.
DR PDBsum; 5YRC; -.
DR PDBsum; 5YRD; -.
DR PDBsum; 6LEE; -.
DR SMR; P11041; -.
DR PRIDE; P11041; -.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0039679; C:viral occlusion body; IEA:UniProtKB-KW.
DR InterPro; IPR008464; Cypo_polyhedrin_Cypovirus1.
DR Pfam; PF05865; Cypo_polyhedrin; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Glycoprotein; Host cytoplasm; Late protein; Signal;
KW Viral occlusion body.
FT SIGNAL 1..27
FT CHAIN 28..248
FT /note="Polyhedrin"
FT /id="PRO_0000040680"
FT CARBOHYD 28
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 77
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 86
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 237
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT VARIANT 101
FT /note="H -> Y (in strain: A)"
FT VARIANT 248
FT /note="Q -> QRLLV (in strain: A)"
FT HELIX 12..29
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 33..42
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 48..63
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 65..68
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 79..90
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 107..113
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 119..121
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 123..127
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 133..136
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 137..139
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 147..149
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 151..155
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 158..167
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 176..183
FT /evidence="ECO:0007829|PDB:5GQI"
FT TURN 191..193
FT /evidence="ECO:0007829|PDB:5GQI"
FT TURN 194..196
FT /evidence="ECO:0007829|PDB:5EXY"
FT HELIX 197..206
FT /evidence="ECO:0007829|PDB:5GQI"
FT STRAND 208..215
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 217..223
FT /evidence="ECO:0007829|PDB:5GQI"
FT HELIX 226..228
FT /evidence="ECO:0007829|PDB:5GQI"
SQ SEQUENCE 248 AA; 28457 MW; 5FCBD6C63B3DD607 CRC64;
MADVAGTSNR DFRGREQRLF NSEQYNYNNS LNGEVSVWVY AYYSDGSVLV INKNSQYKVG
ISETFKALKE YREGQHNDSY DEYEVNQSIY YPNGGDARKF HSNAKPRAIQ IIFSPSVNVR
TIKMAKGNAV SVPDEYLQRS HPWEATGIKY RKIKRDGEIV GYSHYFELPH EYNSISLAVS
GVHKNPSSYN VGSAHNVMDV FQSCDLALRF CNRYWAELEL VNHYISPNAY PYLDINNHSY
GVALSNRQ
