ID   PYM_BOMMO               Reviewed;         193 AA.
AC   Q2F5J3;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Partner of Y14 and mago {ECO:0000250|UniProtKB:P82804};
DE   AltName: Full=Protein wibg homolog;
GN   Name=Pym {ECO:0000250|UniProtKB:P82804}; Synonyms=wibg;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Niu B.L., Meng Z.Q., Weng H.B., Shen W.F., He L.H., Zheng K.F., Ye S.T.,
RA   Lin T.B., Chen J.E.;
RT   "Blast silkworm EST database for functional genes.";
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of the exon junction complex (EJC), a multiprotein
CC       complex that associates immediately upstream of the exon-exon junction
CC       on mRNAs and serves as a positional landmarks for the intron exon
CC       structure of genes and directs post-transcriptional processes in the
CC       cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or
CC       translation. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts (via N-terminus) with mago and tsu/Y14; the
CC       interaction is direct. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. Nuclear export is
CC       mediated by emb/Crm1 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the pym family. {ECO:0000305}.
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DR   EMBL; DQ311430; ABD36374.1; -; mRNA.
DR   RefSeq; NP_001040288.1; NM_001046823.1.
DR   AlphaFoldDB; Q2F5J3; -.
DR   STRING; 7091.BGIBMGA009902-TA; -.
DR   GeneID; 692986; -.
DR   KEGG; bmor:692986; -.
DR   CTD; 692986; -.
DR   eggNOG; KOG4325; Eukaryota.
DR   HOGENOM; CLU_074603_3_0_1; -.
DR   InParanoid; Q2F5J3; -.
DR   OrthoDB; 1545729at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0035145; C:exon-exon junction complex; ISS:UniProtKB.
DR   GO; GO:1903259; P:exon-exon junction complex disassembly; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:UniProtKB.
DR   InterPro; IPR039333; PYM1.
DR   InterPro; IPR015362; WIBG_mago-bd.
DR   InterPro; IPR036348; WIBG_N_sf.
DR   PANTHER; PTHR22959; PTHR22959; 1.
DR   Pfam; PF09282; Mago-bind; 1.
DR   SMART; SM01273; Mago-bind; 1.
DR   SUPFAM; SSF101931; SSF101931; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..193
FT                   /note="Partner of Y14 and mago"
FT                   /id="PRO_0000378161"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          139..192
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        120..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   193 AA;  21858 MW;  29312E3B6BB82F75 CRC64;
     MSTPTAYEHD ADGSKFIPAT QRPDGTWRKP RRIKEGYVPQ EEVPLYESKG KQFRARQNDG
     LPVGLTPEIV AQAQKKKGQR STIQPIPGMI ITVEKKKKKK KTVTGVEEAA EKLAKCEIQE
     PTLPSQSVPT ESISQSDPTK RLKNLRKKLR EIEFLEEKIK AGLLKSPDKD QKEKMSKKNE
     ILNEIDILKN SIL