ID   PYP_CERS4               Reviewed;         124 AA.
AC   Q53226;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Photoactive yellow protein;
DE            Short=PYP;
GN   Name=pyp;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 17027;
RX   PubMed=8670821; DOI=10.1002/j.1460-2075.1996.tb00685.x;
RA   Kort R., Hoff W.D., van West M., Kroon A.R., Hoffer S.M., Vlieg K.H.,
RA   Crielaard W., van Beeumen J.J., Hellingwerf K.J.;
RT   "The xanthopsins: a new family of eubacterial blue-light photoreceptors.";
RL   EMBO J. 15:3209-3218(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHROMOPHORE.
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RX   PubMed=9630474; DOI=10.1016/s0167-4838(98)00050-8;
RA   Kort R., Phillips-Jones M.K., Van Aalten D.M.F., Haker A., Hoffer S.M.,
RA   Hellingwerf K.J., Crielaard W.;
RT   "Sequence, chromophore extraction and 3-D model of the photoactive yellow
RT   protein from Rhodobacter sphaeroides.";
RL   Biochim. Biophys. Acta 1385:1-6(1998).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=RK1;
RX   PubMed=11108842; DOI=10.1016/s0014-5793(00)02242-0;
RA   Haker A., Hendriks J., Gensch T., Hellingwerf K.J., Crielaard W.;
RT   "Isolation, reconstitution and functional characterisation of the
RT   Rhodobacter sphaeroides photoactive yellow protein.";
RL   FEBS Lett. 486:52-56(2000).
CC   -!- FUNCTION: This photoactive protein is a photoreceptor with kinetics
CC       similar to that of rhodopsin.
CC   -!- PTM: The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is
CC       covalently bound via a thioester linkage.
CC   -!- SIMILARITY: Belongs to the photoactive yellow protein family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Although this was cloned from strain NCIB 8253 in 1998 it was
CC       not detected as part of the complete proteome when it was sequenced in
CC       2005. {ECO:0000305}.
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DR   EMBL; X98889; CAA67394.1; -; Genomic_DNA.
DR   EMBL; AJ002398; CAA05377.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q53226; -.
DR   SMR; Q53226; -.
DR   GeneID; 57472332; -.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00130; PAS; 1.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR012130; PYP.
DR   Pfam; PF00989; PAS; 1.
DR   PIRSF; PIRSF000087; PYP; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   TIGRFAMs; TIGR02373; photo_yellow; 1.
PE   1: Evidence at protein level;
KW   Chromophore; Photoreceptor protein; Receptor; Sensory transduction.
FT   CHAIN           1..124
FT                   /note="Photoactive yellow protein"
FT                   /id="PRO_0000144917"
FT   DOMAIN          22..85
FT                   /note="PAS"
FT   MOD_RES         68
FT                   /note="S-(4-hydroxycinnamyl)cysteine"
SQ   SEQUENCE   124 AA;  13979 MW;  4D25A3C27F151142 CRC64;
     MEIIPFGSAD LDNILAREPQ RAEYLPFGAV LLDRTGTILK YNRAEGGIAN RNPADVIGKN
     FFNEIAPCAK GKRFHGEFLR FHQTGQVNVM FDYKFAYKGA NVGVKIHMKS QPDGQSCWLF
     VKRV