ID   PYP_HALSE               Reviewed;         125 AA.
AC   P81046;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Photoactive yellow protein;
DE            Short=PYP;
GN   Name=pyp;
OS   Halochromatium salexigens (Chromatium salexigens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Halochromatium.
OX   NCBI_TaxID=49447;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=8611556; DOI=10.1021/bi951494t;
RA   Koh M., van Driessche G., Samyn B., Hoff W.D., Meyer T.E., Cusanovich M.A.,
RA   van Beeumen J.J.;
RT   "Sequence evidence for strong conservation of the photoactive yellow
RT   proteins from the halophilic phototrophic bacteria Chromatium salexigens
RT   and Rhodospirillum salexigens.";
RL   Biochemistry 35:2526-2534(1996).
CC   -!- FUNCTION: Photoactive blue light protein. Probably functions as a
CC       photoreceptor for a negative phototaxis response (By similarity).
CC       {ECO:0000250}.
CC   -!- PTM: The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is
CC       covalently bound via a thioester linkage.
CC   -!- SIMILARITY: Belongs to the photoactive yellow protein family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P81046; -.
DR   SMR; P81046; -.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00130; PAS; 1.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR012130; PYP.
DR   Pfam; PF00989; PAS; 1.
DR   PIRSF; PIRSF000087; PYP; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   TIGRFAMs; TIGR02373; photo_yellow; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   1: Evidence at protein level;
KW   Chromophore; Direct protein sequencing; Photoreceptor protein; Receptor;
KW   Sensory transduction.
FT   CHAIN           1..125
FT                   /note="Photoactive yellow protein"
FT                   /id="PRO_0000144913"
FT   DOMAIN          23..86
FT                   /note="PAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   MOD_RES         69
FT                   /note="S-(4-hydroxycinnamyl)cysteine"
SQ   SEQUENCE   125 AA;  14063 MW;  6DD02670BD1D2677 CRC64;
     MNIVHFGSDD IENSLANMSD QDLNQLAFGA IQLDASGKVL QYNAAEEGIT GRDPKSVIGK
     NFFEDVAPCT KSQEFQGRFK EGVANGNLAT MFEYVFDYQM KPTKVKVHMK KALVDDSYWI
     FVKRL