ATP6_VIBAL
ID ATP6_VIBAL Reviewed; 270 AA.
AC P12984;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=ATP synthase subunit a {ECO:0000255|HAMAP-Rule:MF_01393};
DE AltName: Full=ATP synthase F0 sector subunit a {ECO:0000255|HAMAP-Rule:MF_01393};
DE AltName: Full=F-ATPase subunit 6 {ECO:0000255|HAMAP-Rule:MF_01393};
GN Name=atpB {ECO:0000255|HAMAP-Rule:MF_01393}; Synonyms=uncB;
OS Vibrio alginolyticus.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=663;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=138-2;
RX PubMed=2529481; DOI=10.1093/nar/17.19.7993;
RA Krumholz L.R., Esser U., Simoni R.D.;
RT "Nucleotide sequence of the unc operon of Vibrio alginolyticus.";
RL Nucleic Acids Res. 17:7993-7994(1989).
RN [2]
RP SIMILARITY TO OTHER A SUBUNITS.
RX PubMed=2147679; DOI=10.1128/jb.172.12.6809-6817.1990;
RA Krumholz L.R., Esser U., Simoni R.D.;
RT "Characterization of the H(+)-pumping F1F0 ATPase of Vibrio
RT alginolyticus.";
RL J. Bacteriol. 172:6809-6817(1990).
CC -!- FUNCTION: Key component of the proton channel; it plays a direct role
CC in the translocation of protons across the membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01393}.
CC -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC - and CF(0) - the membrane proton channel. CF(1) has five subunits:
CC alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main
CC subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an
CC alternating ring which encloses part of the gamma chain. CF(1) is
CC attached to CF(0) by a central stalk formed by the gamma and epsilon
CC chains, while a peripheral stalk is formed by the delta and b chains.
CC {ECO:0000255|HAMAP-Rule:MF_01393}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01393}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01393}.
CC -!- SIMILARITY: Belongs to the ATPase A chain family. {ECO:0000255|HAMAP-
CC Rule:MF_01393}.
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DR EMBL; X16050; CAA34175.1; -; Genomic_DNA.
DR PIR; S06076; S06076.
DR RefSeq; WP_005378922.1; NZ_WAHT01000005.1.
DR AlphaFoldDB; P12984; -.
DR SMR; P12984; -.
DR STRING; 663.BAU10_15110; -.
DR GeneID; 61530837; -.
DR eggNOG; COG0356; Bacteria.
DR OrthoDB; 867266at2; -.
DR BRENDA; 7.1.2.2; 6624.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.120.220; -; 1.
DR HAMAP; MF_01393; ATP_synth_a_bact; 1.
DR InterPro; IPR045082; ATP_syn_F0_a_bact/chloroplast.
DR InterPro; IPR000568; ATP_synth_F0_asu.
DR InterPro; IPR023011; ATP_synth_F0_asu_AS.
DR InterPro; IPR035908; F0_ATP_A_sf.
DR PANTHER; PTHR42823; PTHR42823; 1.
DR Pfam; PF00119; ATP-synt_A; 1.
DR PRINTS; PR00123; ATPASEA.
DR SUPFAM; SSF81336; SSF81336; 1.
DR TIGRFAMs; TIGR01131; ATP_synt_6_or_A; 1.
DR PROSITE; PS00449; ATPASE_A; 1.
PE 3: Inferred from homology;
KW ATP synthesis; Cell inner membrane; Cell membrane; CF(0);
KW Hydrogen ion transport; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..270
FT /note="ATP synthase subunit a"
FT /id="PRO_0000082077"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
SQ SEQUENCE 270 AA; 30134 MW; 1585C82C4C967A6A CRC64;
MAAPGEALTS SGYIAHHLSN LSLYKLGLVG SETSFWNVHI DSLFFSWFTG LIFLGIFYKV
AKRTTAGVPG KLQCAVEMIV EFVADNVKDT FHGRNPLIAP LALTIFCWVF LMNVMDLVPI
DFLPYPAEHW LGIPYLKVVP SADVNITMAM ALGVFALMIY YSIKVKGLGG FAKELALHPF
NHPLMIPFNL LIEVVSLLAK PLSLGMRLFG NMFAGEVVFI LCAAMLPWYL QWMGSLPWAI
FHILVITIQA FVFMMLTIVY LSMAHEDPDH
