ATP8_ARBLI
ID ATP8_ARBLI Reviewed; 54 AA.
AC Q9MJC0;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2001, sequence version 2.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=ATP synthase protein 8;
DE AltName: Full=A6L;
DE AltName: Full=F-ATPase subunit 8;
GN Name=MT-ATP8; Synonyms=ATP8, ATPASE8, MTATP8;
OS Arbacia lixula (Black urchin) (Echinus lixula).
OG Mitochondrion.
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Arbacioida; Arbaciidae; Arbacia.
OX NCBI_TaxID=7640;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Egg;
RX PubMed=8728390; DOI=10.1006/mpev.1996.0027;
RA De Giorgi C., Martiradonna A., Lanave C., Saccone C.;
RT "Complete sequence of the mitochondrial DNA in the sea urchin Arbacia
RT lixula: conserved features of the echinoid mitochondrial genome.";
RL Mol. Phylogenet. Evol. 5:323-332(1996).
CC -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or
CC Complex V) produces ATP from ADP in the presence of a proton gradient
CC across the membrane which is generated by electron transport complexes
CC of the respiratory chain. F-type ATPases consist of two structural
CC domains, F(1) - containing the extramembraneous catalytic core and F(0)
CC - containing the membrane proton channel, linked together by a central
CC stalk and a peripheral stalk. During catalysis, ATP synthesis in the
CC catalytic domain of F(1) is coupled via a rotary mechanism of the
CC central stalk subunits to proton translocation. Part of the complex
CC F(0) domain. Minor subunit located with subunit a in the membrane (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC - and CF(0) - the membrane proton channel. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane; Single-pass membrane
CC protein.
CC -!- SIMILARITY: Belongs to the ATPase protein 8 family. {ECO:0000305}.
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DR EMBL; X80396; CAB93002.1; -; Genomic_DNA.
DR RefSeq; NP_007347.2; NC_001770.1.
DR AlphaFoldDB; Q9MJC0; -.
DR SMR; Q9MJC0; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
DR GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015986; P:proton motive force-driven ATP synthesis; IEA:InterPro.
DR InterPro; IPR001421; ATP8_metazoa.
DR Pfam; PF00895; ATP-synt_8; 1.
PE 3: Inferred from homology;
KW ATP synthesis; CF(0); Hydrogen ion transport; Ion transport; Membrane;
KW Mitochondrion; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..54
FT /note="ATP synthase protein 8"
FT /id="PRO_0000195487"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 54 AA; 6422 MW; A2F8EF28C181B736 CRC64;
MPQLEFTWWI INFFIVWTAD FTLLIVLSIP NLSTPTTLSK QLDINKSHVT WQWS