ID   ATP8_CANPA              Reviewed;          48 AA.
AC   P17345;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=ATP synthase protein 8;
DE   AltName: Full=A6L;
DE   AltName: Full=F-ATPase subunit 8;
GN   Name=ATP8; Synonyms=AAP1;
OS   Candida parapsilosis (Yeast).
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5480;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CBS 7154 / SP1;
RX   PubMed=2143015; DOI=10.1093/nar/18.14.4267;
RA   Guelin E., Velours J., Guerin M.;
RT   "Cloning and sequencing of a fragment of the linear mitochondrial DNA of
RT   the yeast Candida parapsilosis supporting genes encoding subunit 8 of F0
RT   ATP synthase and a putative t-RNA(Pro).";
RL   Nucleic Acids Res. 18:4267-4267(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SR23 / CBS 7157;
RX   PubMed=15449175; DOI=10.1007/s00438-004-1046-0;
RA   Nosek J., Novotna M., Hlavatovicova Z., Ussery D.W., Fajkus J., Tomaska L.;
RT   "Complete DNA sequence of the linear mitochondrial genome of the pathogenic
RT   yeast Candida parapsilosis.";
RL   Mol. Genet. Genomics 272:173-180(2004).
CC   -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or
CC       Complex V) produces ATP from ADP in the presence of a proton gradient
CC       across the membrane which is generated by electron transport complexes
CC       of the respiratory chain. F-type ATPases consist of two structural
CC       domains, F(1) - containing the extramembraneous catalytic core and F(0)
CC       - containing the membrane proton channel, linked together by a central
CC       stalk and a peripheral stalk. During catalysis, ATP synthesis in the
CC       catalytic domain of F(1) is coupled via a rotary mechanism of the
CC       central stalk subunits to proton translocation. Part of the complex
CC       F(0) domain. Minor subunit located with subunit a in the membrane (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC       - and CF(0) - the membrane proton channel. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane; Single-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the ATPase protein 8 family. {ECO:0000305}.
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DR   EMBL; X52115; CAA36361.1; -; Genomic_DNA.
DR   EMBL; X74411; CAE54610.1; -; Genomic_DNA.
DR   PIR; S10465; PWCK8P.
DR   RefSeq; NP_943648.1; NC_005253.2.
DR   AlphaFoldDB; P17345; -.
DR   SMR; P17345; -.
DR   GeneID; 2657790; -.
DR   CGD; CAL0000145092; ATP8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015986; P:proton motive force-driven ATP synthesis; IEA:InterPro.
DR   InterPro; IPR009230; ATP_synth_su8_fun.
DR   Pfam; PF05933; Fun_ATP-synt_8; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; CF(0); Hydrogen ion transport; Ion transport; Membrane;
KW   Mitochondrion; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..48
FT                   /note="ATP synthase protein 8"
FT                   /id="PRO_0000195598"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   48 AA;  5492 MW;  0E7876341CAF0747 CRC64;
     MPQLVPFYFM NLLTGGILAI SLLLYFVATY LLPNILRLLI ARNIIIKL