ID   PYREL_HALSA             Reviewed;         212 AA.
AC   Q9HS16;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=PyrE-like protein;
GN   Name=pyrE1; OrderedLocusNames=VNG_0448G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. {ECO:0000305}.
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DR   EMBL; AE004437; AAG18992.1; -; Genomic_DNA.
DR   PIR; D84203; D84203.
DR   RefSeq; WP_010902287.1; NC_002607.1.
DR   AlphaFoldDB; Q9HS16; -.
DR   SMR; Q9HS16; -.
DR   STRING; 64091.VNG_0448G; -.
DR   PaxDb; Q9HS16; -.
DR   EnsemblBacteria; AAG18992; AAG18992; VNG_0448G.
DR   GeneID; 5953785; -.
DR   KEGG; hal:VNG_0448G; -.
DR   PATRIC; fig|64091.14.peg.336; -.
DR   HOGENOM; CLU_111001_0_0_2; -.
DR   InParanoid; Q9HS16; -.
DR   OMA; DIHVDWS; -.
DR   OrthoDB; 77963at2157; -.
DR   PhylomeDB; Q9HS16; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0004588; F:orotate phosphoribosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0019856; P:pyrimidine nucleobase biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006222; P:UMP biosynthetic process; IBA:GO_Central.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   HAMAP; MF_01214; PyrE_like; 1.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR022854; PyrE-like.
DR   PANTHER; PTHR19278:SF41; PTHR19278:SF41; 1.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transferase.
FT   CHAIN           1..212
FT                   /note="PyrE-like protein"
FT                   /id="PRO_0000110807"
SQ   SEQUENCE   212 AA;  22162 MW;  10F3E695537F3E3E CRC64;
     MKNVDDLIDD AAALADRGLS RGEIADELNV SRETASWLVE RADTNASVAA TDTDDSPRDV
     HVDWSTIGEA GARLSAIGIA LADALRDHSH DVDLVVGIEK AGVPLATATA NELGTDLATY
     TPRKHQWDEG DMADLGGSFS RNFASVEDRD CFVVDDTVTS GTTITETIQA VREAGGTPVA
     CGVLADKQGL GDVDGTPIEA LLQVIRVGSG DD