ID   PYREL_METST             Reviewed;         198 AA.
AC   Q2NEP2;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=PyrE-like protein {ECO:0000255|HAMAP-Rule:MF_01214};
GN   OrderedLocusNames=Msp_1334;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. {ECO:0000255|HAMAP-Rule:MF_01214}.
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DR   EMBL; CP000102; ABC57711.1; -; Genomic_DNA.
DR   RefSeq; WP_011406910.1; NC_007681.1.
DR   AlphaFoldDB; Q2NEP2; -.
DR   SMR; Q2NEP2; -.
DR   STRING; 339860.Msp_1334; -.
DR   EnsemblBacteria; ABC57711; ABC57711; Msp_1334.
DR   GeneID; 41325903; -.
DR   KEGG; mst:Msp_1334; -.
DR   eggNOG; arCOG00028; Archaea.
DR   HOGENOM; CLU_111001_0_0_2; -.
DR   OMA; DIHVDWS; -.
DR   OrthoDB; 77963at2157; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   HAMAP; MF_01214; PyrE_like; 1.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR022854; PyrE-like.
DR   PANTHER; PTHR19278:SF41; PTHR19278:SF41; 1.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transferase.
FT   CHAIN           1..198
FT                   /note="PyrE-like protein"
FT                   /id="PRO_0000298903"
SQ   SEQUENCE   198 AA;  21436 MW;  E0F8AFC80F48AF65 CRC64;
     MKNKLIEKAT ELRNKGLTTG EIADELNISK DTTQWLIMQM TTVNKTKQKQ KPDDFAINWK
     TIGSSSSRMQ YIASALSDMA VEEGVVDAVV GISISGVPFA TIMAEILDAE LAVFHPIKHM
     KNESAQGALS HNFANIKNKT VVIVDDVITS GATITDAIRV CKKNGANPLV VTVLVDKKGL
     DDSDNVPIKS LIKINKVG