ID   ATP8_DROYA              Reviewed;          53 AA.
AC   P03933;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=ATP synthase protein 8;
DE   AltName: Full=A6L;
DE   AltName: Full=F-ATPase subunit 8;
GN   Name=mt:ATPase8; Synonyms=ATP8, ATPase8, Mtatp8;
OS   Drosophila yakuba (Fruit fly).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6306579; DOI=10.1093/nar/11.12.4211;
RA   Clary D.O., Wolstenholme D.R.;
RT   "Nucleotide sequence of a segment of Drosophila mitochondrial DNA that
RT   contains the genes for cytochrome c oxidase subunits II and III and ATPase
RT   subunit 6.";
RL   Nucleic Acids Res. 11:4211-4227(1983).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2317.6 Ivory Coast;
RX   PubMed=3001325; DOI=10.1007/bf02099755;
RA   Clary D.O., Wolstenholme D.R.;
RT   "The mitochondrial DNA molecular of Drosophila yakuba: nucleotide sequence,
RT   gene organization, and genetic code.";
RL   J. Mol. Evol. 22:252-271(1985).
CC   -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or
CC       Complex V) produces ATP from ADP in the presence of a proton gradient
CC       across the membrane which is generated by electron transport complexes
CC       of the respiratory chain. F-type ATPases consist of two structural
CC       domains, F(1) - containing the extramembraneous catalytic core and F(0)
CC       - containing the membrane proton channel, linked together by a central
CC       stalk and a peripheral stalk. During catalysis, ATP synthesis in the
CC       catalytic domain of F(1) is coupled via a rotary mechanism of the
CC       central stalk subunits to proton translocation. Part of the complex
CC       F(0) domain. Minor subunit located with subunit a in the membrane (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC       - and CF(0) - the membrane proton channel. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane; Single-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the ATPase protein 8 family. {ECO:0000305}.
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DR   EMBL; X00924; CAA25441.1; -; Genomic_DNA.
DR   EMBL; X03240; CAA26988.1; -; Genomic_DNA.
DR   PIR; D93477; PWFF8Y.
DR   RefSeq; NP_006905.1; NC_001322.1.
DR   AlphaFoldDB; P03933; -.
DR   SMR; P03933; -.
DR   GeneID; 807633; -.
DR   KEGG; dya:ATP8; -.
DR   CTD; 4509; -.
DR   FlyBase; FBgn0013178; Dyak\mt:ATPase8.
DR   Proteomes; UP000002282; Mitochondrion.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015986; P:proton motive force-driven ATP synthesis; IEA:InterPro.
DR   InterPro; IPR001421; ATP8_metazoa.
DR   Pfam; PF00895; ATP-synt_8; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; CF(0); Hydrogen ion transport; Ion transport; Membrane;
KW   Mitochondrion; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..53
FT                   /note="ATP synthase protein 8"
FT                   /id="PRO_0000195526"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   53 AA;  6338 MW;  6741C69A7E57EF9B CRC64;
     MPQMAPISWL LLFIVFSITF ILFCSINYYS YMPTSPKSNE LKNINLNSMN WKW