ID   PYRX_SYNY3              Reviewed;         441 AA.
AC   P72934;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Probable dihydroorotase-like protein;
DE   AltName: Full=Aspartate carbamoyltransferase 42 kDa non-catalytic chain;
GN   Name=pyrC'; OrderedLocusNames=sll1018;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Non-functional DHOase. {ECO:0000250|UniProtKB:Q59712}.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       DHOase family. PyrC' subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000022; BAA16951.1; -; Genomic_DNA.
DR   PIR; S74800; S74800.
DR   AlphaFoldDB; P72934; -.
DR   SMR; P72934; -.
DR   STRING; 1148.1652025; -.
DR   PaxDb; P72934; -.
DR   EnsemblBacteria; BAA16951; BAA16951; BAA16951.
DR   KEGG; syn:sll1018; -.
DR   eggNOG; COG0044; Bacteria.
DR   InParanoid; P72934; -.
DR   OMA; ASTTWMH; -.
DR   PhylomeDB; P72934; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0004151; F:dihydroorotase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01317; DHOase_IIa; 1.
DR   InterPro; IPR004722; DHOase.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   SUPFAM; SSF51338; SSF51338; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
PE   3: Inferred from homology;
KW   Pyrimidine biosynthesis; Reference proteome.
FT   CHAIN           1..441
FT                   /note="Probable dihydroorotase-like protein"
FT                   /id="PRO_0000147289"
FT   REGION          121..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   441 AA;  48175 MW;  15E893C8F48230B9 CRC64;
     METQCRPQVR CLDPIQGKET RVTVIVRGRA IVAVEDDSYP IPADAAVIPG ENLLLAPSLA
     DLYSYSGEPG YEDRETLSQL VKTAIAGGFG DVAILPNTDP PLDQPQTLQW LKQRLNQIEG
     VNAHHQPPGD PQAENRPDSA PVQCHWWGSV TQGNQGKQLT EWGELDQAGV IGFSDGGAIQ
     DWRLLQRALE YGAIAGKPLA LVPLNLSLRG NGVMREGPLA IQLGLPPDPV MSEAAVIASL
     LELLPHYGTP VHFMRISTAR GVELIVQAKS QGLNCTASVN WHHLLLSNEA IAHGLPPHTP
     HYDPNLRFDP PLGNEGDRLA LIEGVKSGVI DAIAVDHQAF TYEEKTQTFA ETPPGAIGYE
     LVLPCLWQGL VEKNLITPMA LWRALSTNPR RCLGLPEVSN SRILFDPDQA WTLKRGTLQT
     SAYNSPWWNH SLKGRVVAWE S