ID   PYY2_HUMAN              Reviewed;          33 AA.
AC   Q9NRI6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Putative peptide YY-2;
DE            Short=Putative peptide YY2;
DE   Flags: Precursor;
GN   Name=PYY2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX   PubMed=10756099; DOI=10.1006/geno.2000.6132;
RA   Couzens M., Liu M., Tuechler C., Kofler B., Nessler-Menardi C.,
RA   Parker R.M.C., Klocker H., Herzog H.;
RT   "Peptide YY-2 (PYY2) and pancreatic polypeptide-2 (PPY2): species-specific
RT   evolution of novel members of the neuropeptide Y gene family.";
RL   Genomics 64:318-323(2000).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed mainly in the testis and prostate.
CC       {ECO:0000269|PubMed:10756099}.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. A few point mutations in
CC       the signal peptide region of the PYY2 gene and in several other regions
CC       results in destruction of the normal initiation code, generation of an
CC       alternative initiation site and an early stop codon which reduces the
CC       predicated size of the peptide to only 33 amino acids. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF222904; AAF73876.1; -; mRNA.
DR   AlphaFoldDB; Q9NRI6; -.
DR   BioMuta; HGNC:9749; -.
DR   PRIDE; Q9NRI6; -.
DR   GeneCards; PYY2; -.
DR   HGNC; HGNC:9749; PYY2.
DR   MIM; 606637; gene.
DR   neXtProt; NX_Q9NRI6; -.
DR   InParanoid; Q9NRI6; -.
DR   PathwayCommons; Q9NRI6; -.
DR   Pharos; Q9NRI6; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   5: Uncertain;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   PEPTIDE         19..33
FT                   /note="Putative peptide YY-2"
FT                   /id="PRO_0000345968"
SQ   SEQUENCE   33 AA;  3432 MW;  0ADCC698CE0BA038 CRC64;
     MATVLLALLV YLGALVDAYP IKPEAPGEDA FLG