ID   PYY_ANGJA               Reviewed;          97 AA.
AC   Q76CL2;
DT   24-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Peptide YY;
DE   Flags: Precursor;
GN   Name=pyy;
OS   Anguilla japonica (Japanese eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;
OC   Anguilla.
OX   NCBI_TaxID=7937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Intestine;
RX   AGRICOLA=IND43623806; DOI=10.1016/j.aquaculture.2003.12.002;
RA   Kurokawa T., Iinuma N., Unuma T., Tanaka H., Kagawa H., Ohta H., Suzuki T.;
RT   "Development of endocrine system regulating exocrine pancreas and
RT   estimation of feeding and digestive ability in Japanese eel larvae.";
RL   Aquaculture 234:513-525(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   EMBL; AB109557; BAD01501.1; -; mRNA.
DR   AlphaFoldDB; Q76CL2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   3: Inferred from homology;
KW   Amidation; Cleavage on pair of basic residues; Hormone; Neuropeptide;
KW   Secreted; Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   PEPTIDE         29..64
FT                   /note="Peptide YY"
FT                   /id="PRO_0000025393"
FT   PROPEP          68..97
FT                   /note="C-terminal extension"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000025394"
FT   MOD_RES         64
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   97 AA;  11141 MW;  86D4E353E54AEE35 CRC64;
     MAVVLKPWTV LVALVLCLLV CLGTFVDAYP PKPENPGEDA SPEEQAKYYT ALRHYINLIT
     RQRYGKRSSP EGVMSELLFG DNSEHNQRSR YDDSYMW