ID   PYY_CHICK               Reviewed;          37 AA.
AC   P29203;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Peptide YY-like;
DE            Short=PYY;
GN   Name=PYY;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT TYR-37.
RC   STRAIN=White leghorn; TISSUE=Intestine;
RX   PubMed=1446739; DOI=10.1016/0014-5793(92)81196-s;
RA   Conlon J.M., O'Harte F.;
RT   "The primary structure of a PYY-related peptide from chicken intestine
RT   suggests an anomalous site of cleavage of the signal peptide in
RT   preproPYY.";
RL   FEBS Lett. 313:225-228(1992).
CC   -!- FUNCTION: This gut peptide inhibits exocrine pancreatic secretion, has
CC       a vasoconstrictory action and inhibitis jejunal and colonic mobility.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; S26954; S26954.
DR   AlphaFoldDB; P29203; -.
DR   SMR; P29203; -.
DR   InParanoid; P29203; -.
DR   PhylomeDB; P29203; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR   GO; GO:0005179; F:hormone activity; IBA:GO_Central.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IBA:GO_Central.
DR   GO; GO:0031841; F:neuropeptide Y receptor binding; IBA:GO_Central.
DR   GO; GO:0007631; P:feeding behavior; IBA:GO_Central.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IBA:GO_Central.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Reference proteome;
KW   Secreted.
FT   PEPTIDE         1..37
FT                   /note="Peptide YY-like"
FT                   /id="PRO_0000044811"
FT   MOD_RES         37
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000269|PubMed:1446739"
SQ   SEQUENCE   37 AA;  4237 MW;  EA5053EFC4B597CD CRC64;
     AYPPKPESPG DAASPEEIAQ YFSALRHYIN LVTRQRY