PYY_SCYCA
ID PYY_SCYCA Reviewed; 36 AA.
AC P69095; P09473;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 40.
DE RecName: Full=Peptide YY-like;
DE Short=PYY;
DE AltName: Full=Neuropeptide Y-related peptide;
OS Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=7830;
RN [1]
RP PROTEIN SEQUENCE, AMIDATION AT TYR-36, AND SYNTHESIS.
RC TISSUE=Pancreas;
RX PubMed=2019251; DOI=10.1210/endo-128-5-2273;
RA Conlon J.M., Balasubramaniam A., Hazon N.;
RT "Structural characterization and biological activity of a neuropeptide Y-
RT related peptide from the dogfish, Scyliorhinus canicula.";
RL Endocrinology 128:2273-2279(1991).
CC -!- FUNCTION: Elicits an increase in arterial blood pressure.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR PIR; A49743; A49743.
DR AlphaFoldDB; P69095; -.
DR SMR; P69095; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR CDD; cd00126; PAH; 1.
DR InterPro; IPR001955; Pancreatic_hormone-like.
DR InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR PANTHER; PTHR10533; PTHR10533; 1.
DR Pfam; PF00159; Hormone_3; 1.
DR PRINTS; PR00278; PANCHORMONE.
DR SMART; SM00309; PAH; 1.
DR PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Hormone; Secreted.
FT PEPTIDE 1..36
FT /note="Peptide YY-like"
FT /id="PRO_0000044820"
FT MOD_RES 36
FT /note="Tyrosine amide"
FT /evidence="ECO:0000269|PubMed:2019251"
SQ SEQUENCE 36 AA; 4291 MW; 56A6D8CC086660AA CRC64;
YPPKPENPGE DAPPEELAKY YSALRHYINL ITRQRY