ID   PYY_SQUAC               Reviewed;          36 AA.
AC   P69096; P09473;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Peptide YY-like;
DE            Short=PYY;
DE   AltName: Full=Neuropeptide Y-related peptide;
OS   Squalus acanthias (Spiny dogfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Squalomorphii; Squaliformes; Squalidae; Squalus.
OX   NCBI_TaxID=7797;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT TYR-36.
RC   TISSUE=Pancreas;
RA   Pan J.-Z., Shaw C., Halton D.W., Thim L., Johnston C.F., Fairweather I.,
RA   Buchanan K.D.;
RT   "Isolation and primary structure of the peptide Y from the pancreas of the
RT   spiny dogfish, Squalus acanthias.";
RL   Regul. Pept. 35:252-252(1991).
CC   -!- FUNCTION: Elicits an increase in arterial blood pressure.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; A60022; PCDFY.
DR   AlphaFoldDB; P69096; -.
DR   SMR; P69096; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..36
FT                   /note="Peptide YY-like"
FT                   /id="PRO_0000044821"
FT   MOD_RES         36
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   36 AA;  4291 MW;  56A6D8CC086660AA CRC64;
     YPPKPENPGE DAPPEELAKY YSALRHYINL ITRQRY