QAY_NEUAF
ID QAY_NEUAF Reviewed; 536 AA.
AC Q4U3U6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Quinate permease;
DE AltName: Full=Quinate transporter;
GN Name=qa-y;
OS Neurospora africana.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=5143;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Arnett D.R., Asch D.K.;
RT "Sequence analysis of genes of the quinic acid (qa) cluster of two
RT homothallic Neurospora species.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; DQ015972; AAY41161.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4U3U6; -.
DR SMR; Q4U3U6; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0019630; P:quinate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Quinate metabolism; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..536
FT /note="Quinate permease"
FT /id="PRO_0000260163"
FT TOPO_DOM 1..26
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 27..47
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 48..74
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..98
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 120..131
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 153..160
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 161..181
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 182..195
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 217..285
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 307..327
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 328..349
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 350..352
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 374..389
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 390..410
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 411..435
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 436..456
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 457..458
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 459..479
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 480..536
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 516..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 184
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 536 AA; 60073 MW; 5DD29E4264CB90B9 CRC64;
MTLLALKEDR PTPKAVYNWR VYTCAAIASF ASCMIGYDSS FIGTTLALPS FTKEFDFASY
TPGALALLQS NIVSVYQAGA FFGSLFAFAT SYFLGRRRSL IAFSVVFIIG AAIMLAADGQ
RRGVDPIIAG RVLAGIGVGG ASNMVPIYIS ELAPPAVRGR LVGIYELGWQ IGGLVGFWIN
YGVNTTMAPT RSQWLIPFAV QLIPAGLLFL GSFWIPESPR WLFANGRREE AIKVLCWIRN
LEPTDRYIVE EISYIDADLQ RYAREVGKGF WKPFLSLKQP KVRWRFFLGG MLFLWQNGSG
INAINYYSPT VFRSIGITGT NTGFLTTGIF GVVKMVLTII WLLWLVDLVG RRRILFVGAT
GGSLCMWFIG AYIKIAGPGT TKTEEAKLTS GGIAAIFFFY LWTAFYTPSW NGTPWVINSE
MFDQNTRSLG QASAAANNWF WNFIISRFTP QMFIKMEYGV YFFFASLMLL SVVFIYFFIP
ETKSIPLEAM DRLFAIKSVH NANKILMDEL NFDRNPEREQ SSLDEKDRVT QTENAV
