QCRA_GEOTD
ID QCRA_GEOTD Reviewed; 169 AA.
AC Q45657;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Menaquinol-cytochrome c reductase iron-sulfur subunit;
DE AltName: Full=Rieske iron-sulfur protein;
GN Name=qcrA;
OS Geobacillus thermodenitrificans.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX NCBI_TaxID=33940;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K1041;
RX PubMed=8647852; DOI=10.1074/jbc.271.21.12457;
RA Sone N., Tsuchiya N., Inoue M., Noguchi S.;
RT "Bacillus stearothermophilus qcr operon encoding Rieske FeS protein,
RT cytochrome b6, and a novel-type cytochrome c1 of quinol-cytochrome c
RT reductase.";
RL J. Biol. Chem. 271:12457-12462(1996).
CC -!- FUNCTION: Component of the menaquinol-cytochrome c reductase complex.
CC The Rieske protein is a high potential 2Fe-2S protein.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000255|PROSITE-ProRule:PRU00628};
CC Note=Binds 1 [2Fe-2S] cluster per subunit. {ECO:0000255|PROSITE-
CC ProRule:PRU00628};
CC -!- SUBUNIT: The main subunits of the menaquinone:cytochrome c complex are:
CC cytochrome b, the Rieske protein and a cytochrome b/c subunit.
CC -!- SIMILARITY: Belongs to the Rieske iron-sulfur protein family.
CC {ECO:0000305}.
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DR EMBL; D83789; BAA12116.1; -; Genomic_DNA.
DR RefSeq; WP_008879600.1; NZ_PIZS01000087.1.
DR AlphaFoldDB; Q45657; -.
DR STRING; 33940.GTHT12_01704; -.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.102.10.10; -; 1.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR InterPro; IPR014349; Rieske_Fe-S_prot.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR10134; PTHR10134; 1.
DR Pfam; PF00355; Rieske; 1.
DR SUPFAM; SSF50022; SSF50022; 1.
DR PROSITE; PS51296; RIESKE; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW 2Fe-2S; Disulfide bond; Electron transport; Iron; Iron-sulfur;
KW Metal-binding; Oxidoreductase; Transport.
FT CHAIN 1..169
FT /note="Menaquinol-cytochrome c reductase iron-sulfur
FT subunit"
FT /id="PRO_0000127787"
FT DOMAIN 62..160
FT /note="Rieske"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
FT BINDING 102
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
FT BINDING 104
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
FT BINDING 123
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
FT BINDING 126
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
FT DISULFID 107..125
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00628"
SQ SEQUENCE 169 AA; 19144 MW; 49B3773D4290F558 CRC64;
MSDNKHRVTR RQFLNYTLTG VGGFMAAGML MPMLRFAFDP ILRETAGTDM VAVADVKEIT
TEPKRFDFKV KVKDAWYESE EPRSAWVYKD EKGDIIALSP VCKHLGCTVD WNTDKNNPNH
FFCPCHYGLY TKDGTNVPGT PPTAPLDRYE FEVKDGKLYL GKAKPRGEA
